Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis | |
Wei-Feng Wang; Jun-Li Yang![]() | |
刊名 | Electrophoresis
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2019-05 | |
卷号 | 40期号:16-17页码:2075–2083 |
关键词 | Capillary electrophoresis Enzyme inhibitor Immobilization Screening |
DOI | DOI 10.1002/elps.201900013 |
英文摘要 | Capillary electrophoresis (CE) has attracted lots of attention due to its simplicity, low sample consumption, low solvent volume, high resolution, and high speed. Based on these advantages, it has been widely used in enzyme inhibitor screening. There are two main operation modes on enzyme inhibitor screening: off‐line (precapillary enzyme assays) in which process CE was used as an analytical tool; online (in‐capillary enzyme assays) which combined the sample injection, mix, reaction, separation, and detection within a single run. Additionally, diverse of new materials were introduced to immobilize enzyme, which has been coupled with CE for the study of enzyme activity and its inhibitor screening. This review gives an overview of the developments and applications for the CE‐based enzyme inhibitor screening. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.licp.cn/handle/362003/25444] ![]() |
专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
通讯作者 | Jun-Li Yang |
作者单位 | Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences |
推荐引用方式 GB/T 7714 | Wei-Feng Wang,Jun-Li Yang. Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis[J]. Electrophoresis,2019,40(16-17):2075–2083. |
APA | Wei-Feng Wang,&Jun-Li Yang.(2019).Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis.Electrophoresis,40(16-17),2075–2083. |
MLA | Wei-Feng Wang,et al."Advances in Screening Enzyme Inhibitors by Capillary Electrophoresis".Electrophoresis 40.16-17(2019):2075–2083. |
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