Joint Toxicity of Arsenic, Copper and Glyphosate on Behavior, Reproduction and Heat Shock Protein Response in Caenorhabditis elegans

	Joint Toxicity of Arsenic, Copper and Glyphosate on Behavior, Reproduction and Heat Shock Protein Response in Caenorhabditis elegans
	Y. B. Wang, A. N. Ezemaduka, Z. H. Li, Z. Y. Chen and C. T. Song
刊名	Bulletin of Environmental Contamination and Toxicology
	2017
卷号	98 期号:4 页码:465-471
通讯作者	王云彪 Song, Chuantao
中文摘要	The soil nematode Caenorhabditis elegans was used in 24-h acute exposures to arsenic (As), copper (Cu) and glyphosate (GPS) and to mixtures of As/Cu and As/GPS to investigate the effects of mixture exposures in the worms. A synergistic type of interaction was observed for acute toxicity with the As/Cu and As/GPS mixtures. Sublethal 24-h exposures of 1/1000, 1/100 and 1/10 of the LC50 concentrations for As, Cu and GPS individually and for As/Cu and As/GPS mixtures were conducted to observe responses in locomotory behavior (head thrashing), reproduction, and heat shock protein expression. Head thrash frequency and reproduction exhibited concentration dependent decreases in both individual and combined exposures to the tested chemical stressors, and showed synergistic interactions even at micromolar concentrations. Furthermore, the HSP70 protein level was significantly increased following exposure to individual and combined chemical stressors in wild-type C. elegans. Our findings establish for the first time the effects of exposure to As/GPS and As/Cu mixtures in C. elegans.
内容类型	期刊论文
源URL	[http://ir.iga.ac.cn/handle/131322/7633]
专题	东北地理与农业生态研究所_湿地与全球变化学科组_期刊论文
推荐引用方式 GB/T 7714	Y. B. Wang, A. N. Ezemaduka, Z. H. Li, Z. Y. Chen and C. T. Song. Joint Toxicity of Arsenic, Copper and Glyphosate on Behavior, Reproduction and Heat Shock Protein Response in Caenorhabditis elegans[J]. Bulletin of Environmental Contamination and Toxicology,2017,98(4):465-471.
APA	Y. B. Wang, A. N. Ezemaduka, Z. H. Li, Z. Y. Chen and C. T. Song.(2017).Joint Toxicity of Arsenic, Copper and Glyphosate on Behavior, Reproduction and Heat Shock Protein Response in Caenorhabditis elegans.Bulletin of Environmental Contamination and Toxicology,98(4),465-471.
MLA	Y. B. Wang, A. N. Ezemaduka, Z. H. Li, Z. Y. Chen and C. T. Song."Joint Toxicity of Arsenic, Copper and Glyphosate on Behavior, Reproduction and Heat Shock Protein Response in Caenorhabditis elegans".Bulletin of Environmental Contamination and Toxicology 98.4(2017):465-471.