Dispersive liquid-liquid microextraction coupled with capillary electrophoresis for simultaneous determination of sulfonamides with the aid of experimental design

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 山东省海岸带环境工程技术研究中心

	Dispersive liquid-liquid microextraction coupled with capillary electrophoresis for simultaneous determination of sulfonamides with the aid of experimental design
	Wen, Yingying 1,2; Li, Jinhua1 ; Zhang, Weiwei 1; Chen, Lingxin1
刊名	ELECTROPHORESIS
	2011-08-01
卷号	32 期号:16 页码:2131-2138
关键词	CE Dispersive liquid-liquid microextraction Experimental design Sulfonamides Water sample
ISSN号	0173-0835
通讯作者	Chen, LX, Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, CAS,Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China. lxchen@yic.ac.cn
产权排序	[Wen, YY; Li, JH; Zhang, WW; Chen, LX] Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, CAS,Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China; [Wen, YY] Chinese Acad Sci, Grad Univ, Beijing, Peoples R China
中文摘要	A novel method for the simultaneous determination of sulfonamides (SAs) in water samples has been developed by using dispersive liquid-liquid microextraction ( DLLME) coupled with CE. Orthogonal and Box-Behnken designs were employed together to assist the optimization of DLLME parameters, including volumes of extraction and disperser solvents, ionic strength, extraction time, and centrifugation time and speed as variable factors. Under the optimum extraction and detection conditions, successful separation of the five SAs was achieved within 5 min, and excellent analytical performances were attained, such as good linear relationships (R>0.980) between peak area and concentration for each SA from 0.5 to 50 mu g/mL, low limits of detection for the five SAs between 0.020 and 0.570 mu g/mL and the intra-day precisions of migration time below 0.80%. The method recoveries obtained at fortified 10 mu g/mL for three water samples ranged from 53.6 to 94.0% with precisions of 1.23-5.60%. The proposed method proved highly sensitive and selective, rapid, convenient and cost-effective, showing great potential for the simultaneous determination of SAs in water samples.
英文摘要	A novel method for the simultaneous determination of sulfonamides (SAs) in water samples has been developed by using dispersive liquid-liquid microextraction ( DLLME) coupled with CE. Orthogonal and Box-Behnken designs were employed together to assist the optimization of DLLME parameters, including volumes of extraction and disperser solvents, ionic strength, extraction time, and centrifugation time and speed as variable factors. Under the optimum extraction and detection conditions, successful separation of the five SAs was achieved within 5 min, and excellent analytical performances were attained, such as good linear relationships (R>0.980) between peak area and concentration for each SA from 0.5 to 50 mu g/mL, low limits of detection for the five SAs between 0.020 and 0.570 mu g/mL and the intra-day precisions of migration time below 0.80%. The method recoveries obtained at fortified 10 mu g/mL for three water samples ranged from 53.6 to 94.0% with precisions of 1.23-5.60%. The proposed method proved highly sensitive and selective, rapid, convenient and cost-effective, showing great potential for the simultaneous determination of SAs in water samples.
学科主题	Biochemistry & Molecular Biology; Chemistry
研究领域[WOS]	Biochemistry & Molecular Biology ; Chemistry
关键词[WOS]	ATOMIC-ABSORPTION-SPECTROMETRY ; SOLID-PHASE EXTRACTION ; WATER SAMPLES ; FLUORESCENCE DETECTION ; GROUND-WATER ; CHROMATOGRAPHY ; HONEY ; MEAT ; ANTIBIOTICS ; HYDROLYSIS
收录类别	SCI
资助信息	Department of Science and Technology of Shandong Province of China[2008GG20005005]; National Natural Science Foundation of China[20975089]; Chinese Academy of Sciences[KZCX2-EW-206]
语种	英语
WOS记录号	WOS:000294180800008
公开日期	2011-11-11
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/5102]
专题	烟台海岸带研究所_山东省海岸带环境工程技术研究中心
作者单位	1.Chinese Acad Sci, Key Lab Coastal Zone Environm Proc, Shandong Prov Key Lab Coastal Zone Environm Proc, CAS,Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wen, Yingying,Li, Jinhua,Zhang, Weiwei,et al. Dispersive liquid-liquid microextraction coupled with capillary electrophoresis for simultaneous determination of sulfonamides with the aid of experimental design[J]. ELECTROPHORESIS,2011,32(16):2131-2138.
APA	Wen, Yingying,Li, Jinhua,Zhang, Weiwei,&Chen, Lingxin.(2011).Dispersive liquid-liquid microextraction coupled with capillary electrophoresis for simultaneous determination of sulfonamides with the aid of experimental design.ELECTROPHORESIS,32(16),2131-2138.
MLA	Wen, Yingying,et al."Dispersive liquid-liquid microextraction coupled with capillary electrophoresis for simultaneous determination of sulfonamides with the aid of experimental design".ELECTROPHORESIS 32.16(2011):2131-2138.