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The mean first passage time and stochastic resonance in gene transcriptional system with time delay
Feng, Y. L.1; Zhu, J.1; Zhang, M.1; Gao, L. L.1; Liu, Y. F.1; Dong, J. M.2
刊名INTERNATIONAL JOURNAL OF MODERN PHYSICS B
2016-04-30
卷号30页码:11
关键词Gene transcription time delay mean first passage time stochastic resonance
ISSN号0217-9792
DOI10.1142/S0217979216500673
英文摘要In this paper, the gene transcriptional dynamics driven by correlated noises are investigated, where the time delay for the synthesis of transcriptional factor is introduced. The effects of the noise correlation strength and time delay on the stationary probability distribution (SPD), the mean first passage time and the stochastic resonance (SR) are analyzed in detail based on the delay Fokker-Planck equation. It is found that both the time delay and noise correlation strength play important roles in the bistable transcriptional system. The effect of the correlation strength reduces but the time delay enhances the mean first passage time (MFPT). Finally, the SR for this gene transcriptional system is found to be enhanced by the time delay.
WOS关键词BISTABLE KINETIC-MODEL ; DIFFERENTIAL EQUATIONS ; CORRELATED NOISES ; REGULATORY SYSTEM ; 1ST-PASSAGE TIME ; SIMULATION ; FEEDBACK ; DRIVEN ; OSCILLATOR ; EXPRESSION
WOS研究方向Physics
语种英语
出版者WORLD SCIENTIFIC PUBL CO PTE LTD
WOS记录号WOS:000376088700006
内容类型期刊论文
源URL[http://119.78.100.186/handle/113462/42635]  
专题中国科学院近代物理研究所
通讯作者Liu, Y. F.
作者单位1.Lanzhou Univ, Hosp 2, Lanzhou 730000, Peoples R China
2.Chinese Acad Sci, Inst Modern Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Feng, Y. L.,Zhu, J.,Zhang, M.,et al. The mean first passage time and stochastic resonance in gene transcriptional system with time delay[J]. INTERNATIONAL JOURNAL OF MODERN PHYSICS B,2016,30:11.
APA Feng, Y. L.,Zhu, J.,Zhang, M.,Gao, L. L.,Liu, Y. F.,&Dong, J. M..(2016).The mean first passage time and stochastic resonance in gene transcriptional system with time delay.INTERNATIONAL JOURNAL OF MODERN PHYSICS B,30,11.
MLA Feng, Y. L.,et al."The mean first passage time and stochastic resonance in gene transcriptional system with time delay".INTERNATIONAL JOURNAL OF MODERN PHYSICS B 30(2016):11.
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