Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce

doi:10.1016/j.phytol.2015.02.013

	Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce
	Wang, Junfeng 1; Wei, Xiaoyi 2; Qin, Xiaochu 3,4; Chen, Hao 5; Lin, Xiuping 1; Zhang, Tianyu 3,4; Yang, Xianwen 1; Liao, Shengrong 1; Yang, Bin 1; Liu, Juan 1
刊名	PHYTOCHEMISTRY LETTERS
	2015-06
卷号	12 页码:59-62
关键词	Pestalotiopsis vaccinii Structure elucidation COX-2 inhibitory activity
ISSN号	1874-3900
DOI	10.1016/j.phytol.2015.02.013
英文摘要	Two new prenylated phenols vaccinol H (1) and vaccinol I (2), together with three known phenols derivatives 3-5, one glyceride derivative 6, and ergosterol 7 were isolated from endogenous Pestalotiopsis vaccinii (cgmcc3.9199) of mangrove plant Kandelia candel (L.) Druce (Rhizophoraceae). The new structures of 1 and 2 were determined by spectroscopic analyses and circular dichroism (CD) spectra. Most of the isolated compounds (2-6) were tested for their antiviral (EV71), cytotoxic, anti-tuberculosis, and anti-inflammatory effects. Among these compounds, compound 2 exhibited potent COX-2 inhibitory activity with an IC50 value of 16.8 mM. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
资助项目	National Natural Science Foundation of China[31270402] ; National Natural Science Foundation of China[21172230] ; National Natural Science Foundation of China[20902094] ; National Natural Science Foundation of China[41176148] ; National Natural Science Foundation of China[21002110]
WOS关键词	METABOLITES
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000356336400011
内容类型	期刊论文
源URL	[http://ir.fio.com.cn:8080/handle/2SI8HI0U/25347]
专题	自然资源部第一海洋研究所
通讯作者	Liu, Yonghong
作者单位	1.Chinese Acad Sci, South China Sea Inst Oceanol, RNAM Ctr Marine Microbiol, CAS Key Lab Trop Marine Bioresources & Ecol,Guang, Guangzhou 510301, Guangdong, Peoples R China 2.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China 3.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Mol Engn, Guangzhou 510530, Guangdong, Peoples R China 4.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Lab Nat Prod Synth, Guangzhou 510530, Guangdong, Peoples R China 5.State Ocean Adm Republ China, Inst Oceanog 1, Key Lab Marine Bioact Subst, Qingdao 266061, Peoples R China
推荐引用方式 GB/T 7714	Wang, Junfeng,Wei, Xiaoyi,Qin, Xiaochu,et al. Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce[J]. PHYTOCHEMISTRY LETTERS,2015,12:59-62.
APA	Wang, Junfeng.,Wei, Xiaoyi.,Qin, Xiaochu.,Chen, Hao.,Lin, Xiuping.,...&Liu, Yonghong.(2015).Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce.PHYTOCHEMISTRY LETTERS,12,59-62.
MLA	Wang, Junfeng,et al."Two new prenylated phenols from endogenous fungus Pestalotiopsis vaccinii of mangrove plant Kandelia candel (L.) Druce".PHYTOCHEMISTRY LETTERS 12(2015):59-62.