Biological effect and molecular mechanism study of biomaterials based on proteomic research | |
Zhen, Zhen ; Zheng, Yufeng ; Ge, Zigang ; Lai, Chen ; Xi, Tingfei | |
刊名 | JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY |
2017 | |
关键词 | Proteomics Biomaterials Biological effect Molecular mechanism HUMAN DERMAL FIBROBLASTS GOLD NANOPARTICLES SILVER NANOPARTICLES BIOCOMPATIBILITY TITANIUM DIFFERENTIATION SCAFFOLD CELLS |
DOI | 10.1016/j.jmst.2017.01.001 |
英文摘要 | Along with the role transformation of biomaterials from bioinert substitute to regenerative inducer, the biological effect and mechanism of material-organism interaction become more important. Since most of animal tests and cellular experiments stay on the phenomenon description instead of mechanism interpretation, the development of proteomics technologies provides a golden opportunity to uncover the molecular interaction mechanism between biomaterial-organism on whole scale. This review summarizes current application of proteomics in biological effect and mechanism study of biomaterials, and discusses the development and challenges for future studies. (C) 2017 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.; Natural Science Foundation of Guangdong Province, China [2016A030310245, 2016A030310244]; China Postdoctoral Science Foundation [2016M591017]; Key Projects in the National Science & Technology Pillar program [2016YFC1102800]; SCI(E); 中国科学引文数据库(CSCD); ARTICLE; 7; 607-615; 33 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/472381] |
专题 | 工学院 |
推荐引用方式 GB/T 7714 | Zhen, Zhen,Zheng, Yufeng,Ge, Zigang,et al. Biological effect and molecular mechanism study of biomaterials based on proteomic research[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2017. |
APA | Zhen, Zhen,Zheng, Yufeng,Ge, Zigang,Lai, Chen,&Xi, Tingfei.(2017).Biological effect and molecular mechanism study of biomaterials based on proteomic research.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY. |
MLA | Zhen, Zhen,et al."Biological effect and molecular mechanism study of biomaterials based on proteomic research".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY (2017). |
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