Measurement of Viscosity of Unadulterated Human Whole Blood Using a Capillary Pressure-Driven Viscometer | |
Kang, Dongyang ; Wang, Wei ; Lee, Juhyun ; Tai, Yu-Chong ; Hsiai, Tzung K. | |
2015 | |
关键词 | unadulterated human whole blood viscosity capillary pressure-driven viscometer non-Newtonian fluid |
英文摘要 | This paper presents the experimental work on the measurement of unadulterated human whole blood viscosity using a capillary-based microfluidic viscometer. The viscosity was measured by monitoring the time-varying length and mean advancing velocity of the blood column inside the viscometer. A high-aspect-ratio microfluidic channel is preferred for the device geometrical configuration. Theoretical modeling and numerical algorithms were applied to obtain the blood viscosity over a wide range of shear rates. Power law and Carreau-Yasuda models were used to model the non-Newtonian behavior of the human whole blood. The proposed approach is uniquely applicable for small sample volume (<2 mu L), and short measurement time (<2min). A wide range of shear rates (varying from of 71.4s(-1) to 5492.1s(-1)) is produced in a single test.; CPCI-S(ISTP); dkang@caltech.edu; 1-4 |
会议录 | IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) |
语种 | 英语 |
内容类型 | 会议论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/450201] |
专题 | 工学院 |
推荐引用方式 GB/T 7714 | Kang, Dongyang,Wang, Wei,Lee, Juhyun,et al. Measurement of Viscosity of Unadulterated Human Whole Blood Using a Capillary Pressure-Driven Viscometer[C]. 见:. |
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