A Biodegradable Coating Based on Self-Assembled Hybrid Nanoparticles to   Control the Performance of Magnesium

doi:10.1002/macp.201500214

CORC > 北京大学 > 工学院

	A Biodegradable Coating Based on Self-Assembled Hybrid Nanoparticles to Control the Performance of Magnesium
	Sun, Jiadi ; Zhu, Ye ; Meng, Long ; Shi, Tiantian ; Liu, Xiaoya ; Zheng, Yufeng
刊名	MACROMOLECULAR CHEMISTRY AND PHYSICS
	2015
关键词	biodegradable EPD Mg nanocomposite coating self-assembly IN-VIVO CORROSION COMPOSITE COATINGS ELECTROPHORETIC DEPOSITION ORTHOPEDIC APPLICATIONS COLLOIDAL PARTICLES MILD-STEEL ALLOYS ELECTRODEPOSITION HYDROXYAPATITE ACID
DOI	10.1002/macp.201500214
英文摘要	A new biodegradable nanocomposite coating to control the biocompatibility and anticorrosion property of Mg is reported in this work. The key feature of this strategy is to equip the Mg surfaces with poly(gamma-glutamic acid)-g-7-amino-4-methylcoumarin/hydroxyapatite (gamma-PGA-g-AMC/HA) hybrid nanoparticles via electrophoretic deposition in ethanol. The microstructures of the resulting nanocomposite coating are characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy. The results of standard electrochemical measurements along with immersion tests indicate that the nanocomposite coating has preferable in vitro degradation and corrosion resistance behavior than bare Mg. In addition, cytocompatibility is conducted using NIH3T3 cells and the coated sample shows better cell viability and cell adhesion than pure Mg substrate over the whole incubation period. The favorable anticorrosion behavior and cytocompatibility of the nanocomposite coating suggest that the newly developed gamma-PGA-g-AMC/HA biodegradable nanocomposite coating may have a potential to improve the biological performance of Mg-based biomedical implants.; National Nature Science Foundation of China (NSFC) [20974041, 21174056]; Fundamental Research Funds for the Central Universities [JUSRP 51305A]; MOE; SAFEA for 111 Project [B13025]; Jiangsu postgraduate scientific research and innovation plan project [KYLX_1128]; SCI(E); EI; ARTICLE; lxy@jiangnan.edu.cn; 19; 1952-1962; 216
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/415937]
专题	工学院
推荐引用方式 GB/T 7714	Sun, Jiadi,Zhu, Ye,Meng, Long,et al. A Biodegradable Coating Based on Self-Assembled Hybrid Nanoparticles to Control the Performance of Magnesium[J]. MACROMOLECULAR CHEMISTRY AND PHYSICS,2015.
APA	Sun, Jiadi,Zhu, Ye,Meng, Long,Shi, Tiantian,Liu, Xiaoya,&Zheng, Yufeng.(2015).A Biodegradable Coating Based on Self-Assembled Hybrid Nanoparticles to Control the Performance of Magnesium.MACROMOLECULAR CHEMISTRY AND PHYSICS.
MLA	Sun, Jiadi,et al."A Biodegradable Coating Based on Self-Assembled Hybrid Nanoparticles to Control the Performance of Magnesium".MACROMOLECULAR CHEMISTRY AND PHYSICS (2015).