Nanoscale theranostics for physical stimulus-responsive cancer therapies

doi:10.1016/j.blomaterials.2015.09.018

CORC > 北京大学 > 工学院

	Nanoscale theranostics for physical stimulus-responsive cancer therapies
	Chen, Qian ; Ke, Hengte ; Dai, Zhifei ; Liu, Zhuang
刊名	BIOMATERIALS
	2015
关键词	Physical stimulus Theranostics Cancer therapies GUIDED PHOTOTHERMAL THERAPY INTENSITY FOCUSED ULTRASOUND UP-CONVERSION NANOPARTICLES SUPERPARAMAGNETIC IRON-OXIDE NEAR-INFRARED LIGHT VIVO PHOTODYNAMIC THERAPY LOCALIZED PROSTATE-CANCER DRUG-DELIVERY SYSTEM NONINVASIVE RADIOFREQUENCY FIELD COPPER SULFIDE NANOPARTICLES
DOI	10.1016/j.blomaterials.2015.09.018
英文摘要	Physical stimulus-responsive therapies often employing multifunctional theranostic agents responsive to external physical stimuli such as light, magnetic field, ultra-sound, radiofrequency, X-ray, etc., have been widely explored as novel cancer therapy strategies, showing encouraging results in many pre-clinical animal experiments. Unlike conventional cancer chemotherapy which often accompanies with severe toxic side effects, physical stimulus-responsive agents usually are non-toxic by themselves and would destruct cancer cells only under specific external stimuli, and thus could offer greatly reduced toxicity and enhanced treatment specificity. In addition, physical stimulus-responsive therapies can also be combined with other traditional therapeutics to achieve synergistic anti-tumor effects via a variety of mechanisms. In this review, we will summarize the latest progress in the development of physical stimulus-responsive therapies, and discuss the important roles of nanoscale theranostic agents involved in those non-conventional therapeutic strategies. (C) 2015 Elsevier Ltd. All rights reserved.; National Basic Research Programs of China (973 Program) [2012CB932600, 2011CB911002]; National Natural Science Foundation of China [51222203, 51132006]; Juangsu Natural Science Fund for Distinguished Young Scholars [BK20130005]; Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions; SCI(E); EI; PubMed; REVIEW; zliu@suda.edu.cn; 214-230; 73
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/415250]
专题	工学院
推荐引用方式 GB/T 7714	Chen, Qian,Ke, Hengte,Dai, Zhifei,et al. Nanoscale theranostics for physical stimulus-responsive cancer therapies[J]. BIOMATERIALS,2015.
APA	Chen, Qian,Ke, Hengte,Dai, Zhifei,&Liu, Zhuang.(2015).Nanoscale theranostics for physical stimulus-responsive cancer therapies.BIOMATERIALS.
MLA	Chen, Qian,et al."Nanoscale theranostics for physical stimulus-responsive cancer therapies".BIOMATERIALS (2015).