A study of hemorheological behaviour for patients with Alzheimer's disease at the early stages | |
Wen, ZY ; Xie, JX ; Guan, ZW ; Sun, DG ; Yao, WJ ; Chen, K ; Yan, Z ; Mu, QW | |
刊名 | clinical hemorheology and microcirculation |
2000 | |
关键词 | blood viscosity Alzheimer&apos hemorheology HIPPOCAMPAL-FORMATION ATROPHY MRI s disease |
英文摘要 | To evaluate the change of hemorheological indexes for patients with Alzheimer's disease (AD) at the early stages and to discuss effects of these changes on AD, high shear value of whole blood viscosity (eta(bh)), reduced high shear value of whole blood viscosity (r eta(bh)), low shear value of whole blood viscosity (eta(bl)), reduced low shear, value of whole blood viscosity (r eta(bl)), KT value of whole blood viscosity, hematocrit (HCT) and blood plasma viscosity (eta(P)) were measured in 31 patients with probable AD at the early stages and 33 age-matched healthy subjects. There were significant differences of all hemorheological indexes between AD group and control group except HCT. Step discriminant analysis revealed 81.25% of overall group-classified accuracy in a hemorheological discriminant function consisting of eta(bl), r eta(bl), r eta(bh) and HCT. Significant difference of hemorheological indexes existed between AD and age-matched healthy control subjects. The results showed that measurement of hemorheological indexes could be used as one of reference standards of diagnosis in AD.; Hematology; Peripheral Vascular Disease; SCI(E); 8; ARTICLE; 4; 261-266; 22 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/389476] |
专题 | 工学院 |
推荐引用方式 GB/T 7714 | Wen, ZY,Xie, JX,Guan, ZW,et al. A study of hemorheological behaviour for patients with Alzheimer's disease at the early stages[J]. clinical hemorheology and microcirculation,2000. |
APA | Wen, ZY.,Xie, JX.,Guan, ZW.,Sun, DG.,Yao, WJ.,...&Mu, QW.(2000).A study of hemorheological behaviour for patients with Alzheimer's disease at the early stages.clinical hemorheology and microcirculation. |
MLA | Wen, ZY,et al."A study of hemorheological behaviour for patients with Alzheimer's disease at the early stages".clinical hemorheology and microcirculation (2000). |
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