Effect of Co-60 irradiation on characteristics of hemorheology in   rabbits

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	Effect of Co-60 irradiation on characteristics of hemorheology in rabbits
	Wen, ZY ; Xie, LD ; Yan, ZY ; Yao, WJ ; Chen, K ; Ka, WB ; Chien, S
刊名	clinical hemorheology and microcirculation
	2001
关键词	Co-60 irradiation rabbit hemorheological characteristics HEMATOPOIETIC RECONSTITUTION RADIATION APLASIA CHARGE MICE PIG
英文摘要	A high-dose (7 Gy) whole-body Co-60 irradiation for a short period caused disturbances of hematopoietic function. A decrease in the hematocrit of the circulating blood lasted for about 15 days, thus forming an anemic animal model. We studied the influence of high-dose Co-60 irradiation on hemorheologic parameters: percentage of reticulocytes, RBC deformability, sedimentation rate and plasma fibrinogen concentration in the rabbit. It was found that the plasma fibrinogen concentration increased to twice more than control level and that percentage of reticulocytes in circulation disappeared immediately after irradiation. The deformation index of RBCs in shear flow decreased from a value of 58% down to a value of 42% in the first two weeks and gradually returned to control levels about 40 days after Co-60 irradiation. Our results showed that a short period of high-dose Co-60 irradiation caused severe and relatively long-lasting damage of hematopoietic system in animals' body.; Hematology; Peripheral Vascular Disease; SCI(E); PubMed; 3; ARTICLE; 2; 75-81; 25
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/347395]
专题	工学院
推荐引用方式 GB/T 7714	Wen, ZY,Xie, LD,Yan, ZY,et al. Effect of Co-60 irradiation on characteristics of hemorheology in rabbits[J]. clinical hemorheology and microcirculation,2001.
APA	Wen, ZY.,Xie, LD.,Yan, ZY.,Yao, WJ.,Chen, K.,...&Chien, S.(2001).Effect of Co-60 irradiation on characteristics of hemorheology in rabbits.clinical hemorheology and microcirculation.
MLA	Wen, ZY,et al."Effect of Co-60 irradiation on characteristics of hemorheology in rabbits".clinical hemorheology and microcirculation (2001).