Screening on binary Zr-1X (X = Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and   Bi) alloys with good in vitro cytocompatibility and magnetic resonance   imaging compatibility

doi:10.1016/j.actbio.2013.07.035

CORC > 北京大学 > 工学院

	Screening on binary Zr-1X (X = Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and Bi) alloys with good in vitro cytocompatibility and magnetic resonance imaging compatibility
	Zhou, F. Y. ; Qiu, K. J. ; Li, H. F. ; Huang, T. ; Wang, B. L. ; Li, L. ; Zheng, Y. F.
刊名	acta biomaterialia
	2013
关键词	Zr alloys Mechanical property Corrosion Cytocompatibility Magnetic susceptibility OSTEOBLAST-LIKE CELLS DENTAL CASTING ALLOYS ANODIC OXIDE-FILMS CORROSION BEHAVIOR MECHANICAL-PROPERTIES PASSIVE FILMS SURFACE-ROUGHNESS CALCIUM-PHOSPHATE APATITE FORMATION TITANIUM-ALLOYS
DOI	10.1016/j.actbio.2013.07.035
英文摘要	In this study, the microstructures, mechanical properties, corrosion behaviors, in vitro cytocompatibility and magnetic susceptibility of Zr-1X alloys with various alloying elements, including Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and Bi, were systematically investigated to explore their potential use in biomedical applications. The experimental results indicated that annealed Zr-1X alloys consisted entirely or primarily of alpha phase. The alloying elements significantly increased the strength and hardness of pure Zr and had a relatively slight influence on elastic modulus. Ru was the most effective enhancing element and Zr-1Ru alloy had the largest elongation. The results of electrochemical corrosion indicated that adding various elements to Zr improved its corrosion resistance, as indicated by the reduced corrosion current density. The extracts of the studied Zr-1X alloys produced no significant deleterious effects on osteoblast-like cells (MG 63), indicating good in vitro cytocompatibility. All except for Zr-1 Ag alloy showed decreased magnetic susceptibility compared to pure Zr, and Zr-1 Ru alloy had the lowest magnetic susceptibility value, being comparable to that of alpha' phase Zr-Mo alloy and Zr-Nb alloy and far lower than that of Co-Cr alloy and Ti-6Al-4V alloy. Among the experimental Zr-1X alloys, Zr-1Ru alloy possessing high strength coupled with good ductility, good in vitro cytocompatibility and low magnetic susceptibility may be a good candidate alloy for medical devices within a magnetic resonance imaging environment. (C) 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000328592600033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Engineering, Biomedical; Materials Science, Biomaterials; SCI(E); 5; ARTICLE; 12; 9578-9587; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/219121]
专题	工学院
推荐引用方式 GB/T 7714	Zhou, F. Y.,Qiu, K. J.,Li, H. F.,et al. Screening on binary Zr-1X (X = Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and Bi) alloys with good in vitro cytocompatibility and magnetic resonance imaging compatibility[J]. acta biomaterialia,2013.
APA	Zhou, F. Y..,Qiu, K. J..,Li, H. F..,Huang, T..,Wang, B. L..,...&Zheng, Y. F..(2013).Screening on binary Zr-1X (X = Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and Bi) alloys with good in vitro cytocompatibility and magnetic resonance imaging compatibility.acta biomaterialia.
MLA	Zhou, F. Y.,et al."Screening on binary Zr-1X (X = Ti, Nb, Mo, Cu, Au, Pd, Ag, Ru, Hf and Bi) alloys with good in vitro cytocompatibility and magnetic resonance imaging compatibility".acta biomaterialia (2013).