Anomalous diffusion of drug release from a slab matrix: Fractional   diffusion models

doi:10.1016/j.ijpharm.2010.12.009

CORC > 北京大学 > 工学院

	Anomalous diffusion of drug release from a slab matrix: Fractional diffusion models
	Yin, Chen ; Li, Xicheng
刊名	international journal of pharmaceutics
	2011
关键词	Drug release mechanism Mathematical models Anomalous diffusion Fractional calculus Moving boundary problem Exact and approximation solutions SWELLING-CONTROLLED-RELEASE FREE-BOUNDARY PROBLEMS DISPERSED SOLUTE WAVE-EQUATIONS TRANSPORT TIME PHARMACEUTICALS DYNAMICS KINETICS DEVICES
DOI	10.1016/j.ijpharm.2010.12.009
英文摘要	Mathematical models for the release of drug from both non-degradable and degradable slab matrices in which the initial drug loading is greater than the solubility are presented in this paper. Taking the anomalous diffusions in the drug release processes into account, the fractional calculus is introduced to model the related phenomena. To describe different kinds of anomalous diffusions, corresponding fractional diffusion equations are adopted. By employing the integral transform methods, similarity solution method and perturbation method, exact and approximation solutions to the models are obtained. (C) 2010 Elsevier B.V. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296035400009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Pharmacology & Pharmacy; SCI(E); PubMed; 13; ARTICLE; 1,SI; 78-87; 418
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/154014]
专题	工学院
推荐引用方式 GB/T 7714	Yin, Chen,Li, Xicheng. Anomalous diffusion of drug release from a slab matrix: Fractional diffusion models[J]. international journal of pharmaceutics,2011.
APA	Yin, Chen,&Li, Xicheng.(2011).Anomalous diffusion of drug release from a slab matrix: Fractional diffusion models.international journal of pharmaceutics.
MLA	Yin, Chen,et al."Anomalous diffusion of drug release from a slab matrix: Fractional diffusion models".international journal of pharmaceutics (2011).