Chlorella zofingiensis as an Alternative Microalgal Producer of   Astaxanthin: Biology and Industrial Potential

doi:10.3390/md12063487

CORC > 北京大学 > 工学院

	Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential
	Liu, Jin ; Sun, Zheng ; Gerken, Henri ; Liu, Zheng ; Jiang, Yue ; Chen, Feng
刊名	marine drugs
	2014
关键词	astaxanthin Chlorella zofingiensis fed-batch genetic engineering mass cultivation microalgae stress ALGA HAEMATOCOCCUS-PLUVIALIS PHYTOENE DESATURASE GENE DOMINANT SELECTABLE MARKER TRANSGENIC TOMATO PLANTS DIATOM NITZSCHIA-LAEVIS UNICELLULAR GREEN-ALGA HIGH-YIELD PRODUCTION FED-BATCH CULTURE PHAFFIA-RHODOZYMA CAROTENOID BIOSYNTHESIS
DOI	10.3390/md12063487
英文摘要	Astaxanthin (3,3'-dihydroxy-beta,beta-carotene-4,4'-dione), a high-value ketocarotenoid with a broad range of applications in food, feed, nutraceutical, and pharmaceutical industries, has been gaining great attention from science and the public in recent years. The green microalgae Haematococcus pluvialis and Chlorella zofingiensis represent the most promising producers of natural astaxanthin. Although H. pluvialis possesses the highest intracellular astaxanthin content and is now believed to be a good producer of astaxanthin, it has intrinsic shortcomings such as slow growth rate, low biomass yield, and a high light requirement. In contrast, C. zofingiensis grows fast phototrophically, heterotrophically and mixtrophically, is easy to be cultured and scaled up both indoors and outdoors, and can achieve ultrahigh cell densities. These robust biotechnological traits provide C. zofingiensis with high potential to be a better organism than H. pluvialis for mass astaxanthin production. This review aims to provide an overview of the biology and industrial potential of C. zofingiensis as an alternative astaxanthin producer. The path forward for further expansion of the astaxanthin production from C. zofingiensis with respect to both challenges and opportunities is also discussed.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000338189200022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Chemistry, Medicinal; SCI(E); PubMed; 19; REVIEW; jliu@umces.edu; zsun@shou.edu.cn; hgerken@asu.edu; zl2354@columbia.edu; yjiang@hotmail.com.hk; sfchencoe@pku.edu.cn; 6; 3487-3515; 12
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/153821]
专题	工学院
推荐引用方式 GB/T 7714	Liu, Jin,Sun, Zheng,Gerken, Henri,et al. Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential[J]. marine drugs,2014.
APA	Liu, Jin,Sun, Zheng,Gerken, Henri,Liu, Zheng,Jiang, Yue,&Chen, Feng.(2014).Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential.marine drugs.
MLA	Liu, Jin,et al."Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential".marine drugs (2014).