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	FILTRATION MEMBRANE WITH ULTRA-HIGH POROSITY AND PORE SIZE CONTROLLABILITY FABRICATED BY PARYLENE C MOLDING TECHNIQUE FOR TARGETED CELL SEPARATION FROM BRONCHOALVEOLAR LAVAGE FLUID (BALF)
	Liu, Y. ; Wang, W. ; Wu, W. ; Li, H. ; Yang, F. ; Wang, W.
	2015
关键词	Filtration membrane Parylene C molding Ultra-high porosity Cell separation BALF
英文摘要	This paper presented an effective fabrication strategy to prepare micropore arrayed membrane with ultra-high porosity and pore size controllability based on a Parylene C molding technique. The prepared filtration membrane had small supporting structure between adjacent micropores with width of 4 mu m and thereby an ultra-high porosity up to 90.9%. The membrane was 10 mu m thick and had a considerable mechanical strength. The aspect ratio even went to 7.5 in small micropore devices (pore size of 1.39 +/- 0.067 mu m). Bronchoalveolar lavage fluid (BALF) with sparked rare cancer cells was sequentially filtrated through membranes with different pore sizes in an integrated device. The preliminary results indicated that the present multiplex filtration device can get a high targeted cell separation yield of 96.5% and purity of 100% with throughput as high as 2 mL/min.; CPCI-S(ISTP); w.wang@pku.edu.cn; 1767-1769
语种	英语
出处	18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)
内容类型	其他
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/450299]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Liu, Y.,Wang, W.,Wu, W.,et al. FILTRATION MEMBRANE WITH ULTRA-HIGH POROSITY AND PORE SIZE CONTROLLABILITY FABRICATED BY PARYLENE C MOLDING TECHNIQUE FOR TARGETED CELL SEPARATION FROM BRONCHOALVEOLAR LAVAGE FLUID (BALF). 2015-01-01.

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