QQ客服 官方微博 反馈留言

	TRACE LEVEL DETECTION OF NERVE AGENT SIMULANT BY USING CANTILEVER-BASED APTASENSOR
	Zhao, R. ; Wen, Y. ; Yu, X.
	2015
关键词	Piezoresistive cantilevers aptasensor DMMP surface functionalization LOD CHEMICAL WARFARE AGENTS SENSORS
英文摘要	This paper reports a piezoresistive (PZR) cantilever aptasensor for a sensitive and specific detection of dimethyl methylphosphonate (DMMP), a representative simulant of sarin and organophosphorus pesticides (OPPs), in neutral solution for the first time. By improving the design and fabrication processes, the output fluctuation of the PZR cantilever has been decreased to 1 mu V at a 3 V bias voltage. Aptasensor functionalized by a 78-mer 5'-biotinylated aptamer not only realized the trace detection of DMMP with a limit of detection (LOD) of ppb level, but also showed excellent specific response. Finally, a kinetic model based on pseudo-first-order kinetics was developed to analyze the aptamer/DMMP interactions of the PZR cantilever sensors.; CPCI-S(ISTP); yuxm@pku.edu.cn; 1487-1490
语种	英语
出处	18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)
内容类型	其他
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/450296]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Zhao, R.,Wen, Y.,Yu, X.. TRACE LEVEL DETECTION OF NERVE AGENT SIMULANT BY USING CANTILEVER-BASED APTASENSOR. 2015-01-01.

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。