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	Sensing at the nanoparticle trapped tip of funnel nanochannel
	Huang, J. ; Li, S.W. ; Zhang, R. ; Wang, W.
	2015
英文摘要	This paper explored the ion transportation in a funnel nanochannel with nanoparticles trapped at the tip and its applicability in nucleic acid detection. Simulation showed that H+distribution in funnel nanochannel was extremely sensitive to the surface charge density of nanoparticle trapped at the tip, which contributed to the reported high sensitivity. A high sensitivity of 1fM for biotin was achieved in 100μM KCl solution. Sensing capability of 22 mer ssDNA and 22 bp dsDNA was also proved for the first time, which provided a potential application in highly sensitive microRNA detection on chip. ? 2015 IEEE.; EI; 533-535
语种	英语
出处	18th International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2015
DOI标识	10.1109/TRANSDUCERS.2015.7180978
内容类型	其他
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/436758]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Huang, J.,Li, S.W.,Zhang, R.,et al. Sensing at the nanoparticle trapped tip of funnel nanochannel. 2015-01-01.

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