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	Nanofluidic sensing at normal physiological condition by coupling ion concentration polarization with a limit of detection of one femtomole
	Ouyang, Wei ; Wang, Wei ; Zhang, Haixia Alice ; Wu, Wengang ; Li, Zhihong
	2014
英文摘要	Traditional nanofluidic devices lose function at normal physiological condition (e.g. 0.1 M), because the thickness of electrical-double-layer (EDL) ??D (??1 nm) under this circumstance is much smaller than typical nanochannel size, which significantly limits their clinical applications. This work enables nanofluidic sensing of Biotin at normal physiological condition by coupling ion concentration polarization (ICP) with nanofluidic crystal (NFC), which utilizes the enrichment effect for target preconcentration and the depletion effect for buffer desalination, with a limit of detection of 1 fM. ? 2014 IEEE.; EI; CPCI-S(ISTP); 0
语种	英语
DOI标识	10.1109/MEMSYS.2014.6765629
内容类型	其他
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/295147]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Ouyang, Wei,Wang, Wei,Zhang, Haixia Alice,et al. Nanofluidic sensing at normal physiological condition by coupling ion concentration polarization with a limit of detection of one femtomole. 2014-01-01.

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