Association between size-segregated particles in ambient air and acute   respiratory inflammation

doi:10.1016/j.scitotenv.2016.04.196

CORC > 北京大学 > 环境科学与工程学院

	Association between size-segregated particles in ambient air and acute respiratory inflammation
	Han, Yiqun ; Zhu, Tong ; Guan, Tianjia ; Zhu, Yi ; Liu, Jun ; Ji, Yunfang ; Gao, Shuna ; Wang, Fei ; Lu, Huimin ; Huang, Wei
刊名	SCIENCE OF THE TOTAL ENVIRONMENT
	2016
关键词	Size-segregated particles Ultrafine particles Aitken-mode particles Respiratory inflammation Elderly HYDROXYL RADICAL GENERATION EXHALED NITRIC-OXIDE ULTRAFINE PARTICLES PARTICULATE MATTER NUMBER CONCENTRATIONS POLLUTION HEALTH MORTALITY EXPOSURE AIRWAYS
DOI	10.1016/j.scitotenv.2016.04.196
英文摘要	The health effects of particulate matter (PM) in ambient air are well documented. However, whether PM size plays a critical role in these effects is unclear in the population studies. This study investigated the association between the ambient concentrations of PM with varies sizes (5.6-560 nm) and a biomarker of acute respiratory inflammation, the fraction of exhaled nitric oxide (FENO), in a panel of 55 elderly people in Shanghai, China. Linear mixed-effect model was fitted to estimate the association between FENO and moving average concentrations of PM, adjusting for temperature, relative humidity, day of the week, and age. Results showed that among the measured particles size range, Aitken-mode (20-100 nm) particles had the strongest positive association with increased FENO when using moving average concentration of PM up to 24 h prior to visits. The estimates were robust to the adjustment for gender, condition of chronic disease and use of medication, and to the sensitive analysis using different times of visits. The authors concluded that the association between acute respiratory inflammation and PM concentration of fine particulates depended on particle size, and suggested Aitken-mode particles may be the most responsible for this adverse health association. (C) 2016 Elsevier B.V. All rights reserved.; National Natural Science Foundation Committee of China [21190051, 41421064, 41121004]; Chinese Ministry of Science and Technology [2015CB553401, 2008AA062503]; Australia-China Centre for Air Quality Science and Management (ACC-AQSM); SCI(E); EI; PubMed; ARTICLE; yiqunhs@126.com; tzhu@pku.edu.cn; 412-419; 565
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/433738]
专题	环境科学与工程学院
推荐引用方式 GB/T 7714	Han, Yiqun,Zhu, Tong,Guan, Tianjia,et al. Association between size-segregated particles in ambient air and acute respiratory inflammation[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2016.
APA	Han, Yiqun.,Zhu, Tong.,Guan, Tianjia.,Zhu, Yi.,Liu, Jun.,...&Huang, Wei.(2016).Association between size-segregated particles in ambient air and acute respiratory inflammation.SCIENCE OF THE TOTAL ENVIRONMENT.
MLA	Han, Yiqun,et al."Association between size-segregated particles in ambient air and acute respiratory inflammation".SCIENCE OF THE TOTAL ENVIRONMENT (2016).