Circular RNAs: Regulators of Cancer-Related Signaling Pathways and   Potential Diagnostic Biomarkers for Human Cancers

doi:10.7150/thno.19016

CORC > 北京大学 > 生命科学学院

	Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers
	Yang, Zuozhang ; Xie, Lin ; Han, Lei ; Qu, Xin ; Yang, Yihao ; Zhang, Ya ; He, Zewei ; Wang, Yu ; Li, Jing
刊名	THERANOSTICS
	2017
关键词	circular RNA cancer diagnosis biomarkers LONG NONCODING RNA WNT/BETA-CATENIN PATHWAY EXON CIRCULARIZATION GASTRIC-CANCER MESSENGER-RNA CELL-GROWTH HEPATOCELLULAR-CARCINOMA CIRCRNA BIOGENESIS PROFILING REVEALS ESOPHAGEAL CANCER
DOI	10.7150/thno.19016
英文摘要	Circular RNAs (circRNAs) are newly discovered endogenous non-coding RNAs featuring structural stability, high abundance, and tissue-specific expression. CircRNAs are prevalent and conserved in mammalian cells. They are involved in cellular processes and regulate gene expression at the transcriptional or post-transcriptional level by interacting with microRNAs (miRNAs) and other molecules. Recent studies have shown that circRNAs play an important role in the progression of various human diseases including atherosclerosis, nervous system disorders, diabetes, and cancer. In this review, we summarize the advances on endogenous circRNAs in eukaryotic cells and elucidate their diagnostic and prognostic significance in human cancers. Especially, we highlight the involvement of circRNAs in signal transduction pathways as well as their clinical potential to serve as biomarkers.; SCI(E); REVIEW; 12; 3106-3117; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/475895]
专题	生命科学学院
推荐引用方式 GB/T 7714	Yang, Zuozhang,Xie, Lin,Han, Lei,et al. Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers[J]. THERANOSTICS,2017.
APA	Yang, Zuozhang.,Xie, Lin.,Han, Lei.,Qu, Xin.,Yang, Yihao.,...&Li, Jing.(2017).Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers.THERANOSTICS.
MLA	Yang, Zuozhang,et al."Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers".THERANOSTICS (2017).