Cyclic (di)nucleotides: the common language shared by microbe and host | |
Gao, Juyi ; Tao, Jianli ; Liang, Weili ; Jiang, Zhengfan | |
刊名 | CURRENT OPINION IN MICROBIOLOGY |
2016 | |
关键词 | C-DI-GMP PSEUDOMONAS-AERUGINOSA MYCOBACTERIUM-TUBERCULOSIS AMP SYNTHASE STRUCTURAL BIOCHEMISTRY BACTERIAL 2ND-MESSENGER ESCHERICHIA-COLI IMMUNE-RESPONSE PROTEIN REVEALS CYTOSOLIC DNA |
DOI | 10.1016/j.mib.2015.12.005 |
英文摘要 | Fluency in a common language allows individuals to convey information and carry out complex activities that otherwise would be difficult or even impossible without the benefit of shared communication. Cyclic (di)nucleotides have recently been recognized as such an accessible language understood by both microbe and the host, ever since remarkable progresses have revealed the molecular details of these nucleotide second messengers used in cellular communication systems. Though undergoing separate evolutionary pathways in prokaryotes and eukaryotes, cyclic (di)nucleotides enable microbes to influence host cells immediately and fiercely by modulating a variety of cellular activities. Here we highlight recent insights in cyclic (di)nucleotides and focus on the balancing of these indispensable signaling molecules by synthases and phosphodiesterases.; National Natural Science Foundation of China [31230023, 91129000]; Chinese Ministry of Science and Technology [2015CC040097, 2014CB542600]; SCI(E); PubMed; REVIEW; jiangzf@pku.edu.cn; 79-87; 30 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/434966] |
专题 | 生命科学学院 |
推荐引用方式 GB/T 7714 | Gao, Juyi,Tao, Jianli,Liang, Weili,et al. Cyclic (di)nucleotides: the common language shared by microbe and host[J]. CURRENT OPINION IN MICROBIOLOGY,2016. |
APA | Gao, Juyi,Tao, Jianli,Liang, Weili,&Jiang, Zhengfan.(2016).Cyclic (di)nucleotides: the common language shared by microbe and host.CURRENT OPINION IN MICROBIOLOGY. |
MLA | Gao, Juyi,et al."Cyclic (di)nucleotides: the common language shared by microbe and host".CURRENT OPINION IN MICROBIOLOGY (2016). |
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