The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-Mediated   Plant Defense and Development

doi:10.1371/journal.pgen.1003653

CORC > 北京大学 > 生命科学学院

	The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-Mediated Plant Defense and Development
	Song, Susheng ; Qi, Tiancong ; Fan, Meng ; Zhang, Xing ; Gao, Hua ; Huang, Huang ; Wu, Dewei ; Guo, Hongwei ; Xie, Daoxin
刊名	plos genetics
	2013
关键词	TRANSCRIPTION FACTOR FAMILY ARABIDOPSIS-THALIANA GENE-EXPRESSION METHYL JASMONATE SALICYLIC-ACID SIGNALING CASCADE JAZ REPRESSORS PROTEINS RESPONSES BIOSYNTHESIS
DOI	10.1371/journal.pgen.1003653
英文摘要	Plants have evolved sophisticated systems for adaptation to their natural habitat. In response to developmental and environmental cues, plants produce and perceive jasmonate (JA) signals, which induce degradation of JASMONATE-ZIM-Domain (JAZ) proteins and derepress the JAZ-repressed transcription factors to regulate diverse aspects of defense responses and developmental processes. Here, we identified the bHLH subgroup IIId transcription factors (bHLH3, bHLH13, bHLH14 and bHLH17) as novel targets of JAZs. These bHLH subgroup IIId transcription factors act as transcription repressors and function redundantly to negatively regulate JA responses. The quadruple mutant bhlh3 bhlh13 bhlh14 bhlh17 showed severe sensitivity to JA-inhibited root growth and JA-induced anthocyanin accumulation, and exhibited obvious increase in JA-regulated plant defense against pathogen infection and insect attack. Transgenic plants overexpressing bHLH13 or bHLH17 displayed reduced JA responses. Furthermore, these bHLH factors functioned as transcription repressors to antagonize the transcription activators, such as MYC2 and the WD-repeat/bHLH/MYB complex, through binding to their target sequences. Coordinated regulation of JA responses by transcription activators and repressors would benefit plants by allowing fine regulation of defense and development, and survival in their frequently changing environment.; Genetics & Heredity; SCI(E); 27; ARTICLE; 7; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/391417]
专题	生命科学学院
推荐引用方式 GB/T 7714	Song, Susheng,Qi, Tiancong,Fan, Meng,et al. The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-Mediated Plant Defense and Development[J]. plos genetics,2013.
APA	Song, Susheng.,Qi, Tiancong.,Fan, Meng.,Zhang, Xing.,Gao, Hua.,...&Xie, Daoxin.(2013).The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-Mediated Plant Defense and Development.plos genetics.
MLA	Song, Susheng,et al."The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-Mediated Plant Defense and Development".plos genetics (2013).