Computational identification of plant transcription factors and the construction of the PlantTFDB database

doi:10.1007/978-1-60761-854-6_21

CORC > 北京大学 > 生命科学学院

	Computational identification of plant transcription factors and the construction of the PlantTFDB database
	He Kun ; Guo An-Yuan ; Gao Ge ; Zhu Qi-Hui ; Liu Xiao-Chuan ; Zhang He ; Chen Xin ; Gu Xiaocheng ; Luo Jingchu
刊名	methods in molecular biology clifton n j
	2010
DOI	10.1007/978-1-60761-854-6_21
英文摘要	Transcription factors (TFs) play an important role in gene regulation. Computational identification and annotation of TFs at genome scale are the first step toward understanding the mechanism of gene expression and regulation. We started to construct the database of Arabidopsis TFs in 2005 and developed a pipeline for systematic identification of plant TFs from genomic and transcript sequences. In the following years, we built a database of plant TFs (PlantTFDB, http://planttfdb.cbi.pku.edu.cn ) which contains putative TFs identified from 22 species including five model organisms and 17 economically important plants with available EST sequences. To provide comprehensive information for the putative TFs, we made extensive annotation at both the family and gene levels. A brief introduction and key references were presented for each family. Functional domain information and cross-references to various well-known public databases were available for each identified TF. In addition, we predicted putative orthologs of the TFs in other species. PlantTFDB has a simple interface to allow users to make text queries, or BLAST searches, and to download TF sequences for local analysis. We hope that PlantTFDB could provide the user community with a useful resource for studying the function and evolution of transcription factors.; PubMed; 0; 351-68; 674
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/343913]
专题	生命科学学院
推荐引用方式 GB/T 7714	He Kun,Guo An-Yuan,Gao Ge,et al. Computational identification of plant transcription factors and the construction of the PlantTFDB database[J]. methods in molecular biology clifton n j,2010.
APA	He Kun.,Guo An-Yuan.,Gao Ge.,Zhu Qi-Hui.,Liu Xiao-Chuan.,...&Luo Jingchu.(2010).Computational identification of plant transcription factors and the construction of the PlantTFDB database.methods in molecular biology clifton n j.
MLA	He Kun,et al."Computational identification of plant transcription factors and the construction of the PlantTFDB database".methods in molecular biology clifton n j (2010).