DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated   cellular responses in Arabidopsis

doi:10.1007/s11103-014-0247-0

CORC > 北京大学 > 生命科学学院

	DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis
	Kim, Sang-Hoon ; Kim, Hani ; Seo, Kyoung-In ; Kim, Soon-Hee ; Chung, Sunglan ; Huang, Xi ; Yang, Panyu ; Deng, Xing Wang ; Lee, Jae-Hoon
刊名	植物分子生物学
	2014
关键词	CRL4 UV-B DHU1 Arabidopsis SYNTHASE GENE-EXPRESSION E3 UBIQUITIN LIGASES TRANSCRIPTION FACTOR SIGNAL-TRANSDUCTION INDUCED PHOTOMORPHOGENESIS CIRCADIAN CLOCK FEEDBACK-REGULATION STRESS ACCLIMATION DEFENSE RESPONSES BINDING PROTEINS
DOI	10.1007/s11103-014-0247-0
英文摘要	Among T-DNA insertion mutants of various cullin4-RING ubiquitin E3 ligase (CRL4) substrate receptors, one mutant that exhibits enhanced sensitivity in response to ultraviolet-B (UV-B) illumination has been isolated and its corresponding gene has been named DWD HYPERSENSITIVE TO UV-B 1 (DHU1) in Arabidopsis. dhu1 lines showed much shorter hypocotyls than those in wild type under low doses of UV-B. Other light did not alter hypocotyl growth patterns in dhu1, indicating the hypersensitivity of dhu1 is restricted to UV-B. DHU1 was upregulated by more than two times in response to UV-B application of 1.5 mu mol m(-2) s(-1), implying its possible involvement in UV-B signaling. DHU1 is able to bind to DDB1, an adaptor of CRL4; accordingly, DHU1 is thought to act as a substrate receptor of CRL4. Microarray data generated from wild-type and dhu1 under low doses of UV-B revealed that 209 or 124 genes were upregulated or downregulated by more than two times in dhu1 relative to wild type, respectively. About 23.4 % of the total upregulated genes in dhu1 were upregulated by more than five times in response to UV-B based on the AtGenExpress Visualization Tool data, while only about 1.4 % were downregulated to the same degree by UV-B, indicating that loss of DHU1 led to the overall enhancement of the upregulation of UV-B inducible genes. dhu1 also showed altered responsiveness under high doses of UV-B. Taken together, these findings indicate that DHU1 is a potent CRL4 substrate receptor that may function as a negative regulator of UV-B response in Arabidopsis.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000345093800001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemistry & Molecular Biology; Plant Sciences; SCI(E); 2; ARTICLE; jhlee72@pusan.ac.kr; 6; 571-583; 86
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/207749]
专题	生命科学学院
推荐引用方式 GB/T 7714	Kim, Sang-Hoon,Kim, Hani,Seo, Kyoung-In,et al. DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis[J]. 植物分子生物学,2014.
APA	Kim, Sang-Hoon.,Kim, Hani.,Seo, Kyoung-In.,Kim, Soon-Hee.,Chung, Sunglan.,...&Lee, Jae-Hoon.(2014).DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis.植物分子生物学.
MLA	Kim, Sang-Hoon,et al."DWD HYPERSENSITIVE TO UV-B 1 is negatively involved in UV-B mediated cellular responses in Arabidopsis".植物分子生物学 (2014).