Apoptosis of mouse liver nuclei induced in the cytosol of carrot cells

doi:10.1016/S0014-5793(99)00352-X

CORC > 北京大学 > 生命科学学院

	Apoptosis of mouse liver nuclei induced in the cytosol of carrot cells
	Zhao, Y ; Jiang, ZF ; Sun, YL ; Zhai, ZH
刊名	欧洲生化学会联合会快报
	1999
关键词	apoptosis carrot cell cytosol nucleus lamin CYTOCHROME-C FREE-EXTRACTS IN-VITRO DEATH ACTIVATION INDUCTION PATHWAYS PROGRAM EVENTS DATP
DOI	10.1016/S0014-5793(99)00352-X
英文摘要	We report here the apoptosis of mouse liver nuclei induced in the cytosol of carrot cells by cytochrome c. Several typical characteristics of apoptosis, such as chromatin condensation, margination and apoptotic bodies, were detected. The result of DNA gel electrophoresis showed that DNA was degraded into nucleosomal fragments. The terminal deoxynucleotidyl transferase-mediated dUTP-digoxigenin nick end labelling procedure was also performed to detect the breakage of 3'-OH ends of a DNA strand. Furthermore, we found that nuclear lamins were degraded from 88 kDa and 66 kDa to 37 kDa and 47 kDa fragments. The DNA fragmentation could be inhibited by AC-DEVD-CHO and AC-YVAD-CHO. The results indicate that the apoptosis in plant cells may share some similar pathways to apoptosis in animal cells. (C) 1999 Federation of European Biochemical Societies.; Biochemistry & Molecular Biology; Biophysics; Cell Biology; SCI(E); PubMed; 32; ARTICLE; 1; 197-200; 448
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/202010]
专题	生命科学学院
推荐引用方式 GB/T 7714	Zhao, Y,Jiang, ZF,Sun, YL,et al. Apoptosis of mouse liver nuclei induced in the cytosol of carrot cells[J]. 欧洲生化学会联合会快报,1999.
APA	Zhao, Y,Jiang, ZF,Sun, YL,&Zhai, ZH.(1999).Apoptosis of mouse liver nuclei induced in the cytosol of carrot cells.欧洲生化学会联合会快报.
MLA	Zhao, Y,et al."Apoptosis of mouse liver nuclei induced in the cytosol of carrot cells".欧洲生化学会联合会快报 (1999).