Phylogenetic and biochemical studies reveal a potential evolutionary   origin of small heat shock proteins of animals from bacterial class A

doi:10.1007/s00239-005-0076-5

CORC > 北京大学 > 生命科学学院

	Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A
	Fu, XM ; Jiao, WW ; Chang, ZY
刊名	分子演化杂志
	2006
关键词	chaperone small heat shock protein oligomer polydisperse monodisperse ALPHA-CRYSTALLIN CHAPERONE ACTIVITY SUBUNIT EXCHANGE QUATERNARY STRUCTURE METHANOCOCCUS-JANNASCHII MOLECULAR CHAPERONES OLIGOMER FORMATION IN-VITRO PLANTS COMPLEXES
DOI	10.1007/s00239-005-0076-5
英文摘要	Small heat shock proteins ( sHSPs), as one subclass of molecular chaperones, are important for cells to protect proteins under stress conditions. Unlike the large HSPs ( represented by Hsp60 and Hsp70), sHSPs are highly divergent in both primary sequences and oligomeric status, with their evolutionary relationships being unresolved. Here the phylogenetic analysis of a representative 51 sHSPs ( covering the six subfamilies: bacterial class A, bacterial class B, archae, fungi, plant, and animal) reveals a close relationship between bacterial class A and animal sHSPs which form an outgroup. Accumulating data indicate that the oligomers from bacterial class A and animal sHSPs appear to exhibit polydispersity, while those from the rest exhibit monodispersity. Together, the close evolutionary relationship and the similarity in oligomeric polydispersity between bacterial class A and animal sHSPs not only suggest a potential evolutionary origin of the latter from the former, but also imply that their oligomeric polydispersity is somehow a property determined by their primary sequences.; Biochemistry & Molecular Biology; Evolutionary Biology; Genetics & Heredity; SCI(E); PubMed; 22; ARTICLE; 3; 257-266; 62
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/199343]
专题	生命科学学院
推荐引用方式 GB/T 7714	Fu, XM,Jiao, WW,Chang, ZY. Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A[J]. 分子演化杂志,2006.
APA	Fu, XM,Jiao, WW,&Chang, ZY.(2006).Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A.分子演化杂志.
MLA	Fu, XM,et al."Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A".分子演化杂志 (2006).