Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa

doi:10.1016/j.febslet.2012.06.036

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	Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa
	Zhang, Heng ; Gao, Zeng-Qiang ; Su, Xiao-Dong ; Dong, Yu-Hui
刊名	欧洲生化学会联合会快报
	2012
关键词	DIAMINO ACID ENDOPEPTIDASE ESCHERICHIA-COLI PROTEIN SECRETION ANTITOXIN TOXIN RECOGNITION BACTERIAL SEQUENCE REVEALS
DOI	10.1016/j.febslet.2012.06.036
英文摘要	The type VI secretion systems (T6SS) have emerging roles in interspecies competition. In order to have an advantage in defense against other organisms, this system in Pseudomonas aeruginosa delivers a peptidoglycan amidase (Tse1) to the periplasmic space of a competitor. An immune protein (Tsi1) is also produced by the bacterium to protect itself from damage caused by Tse1. Tsi1 directly interacts with Tse1. We report that the crystal structure of Tse1 displays a common CHAP protein fold. Strikingly, our structures showed that the third residue in the catalytic triad may be novel as this residue type has not been observed previously. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000309314200031&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemistry & Molecular Biology; Biophysics; Cell Biology; SCI(E); PubMed; 11; ARTICLE; 19; 3193-3199; 586
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/191138]
专题	生命科学学院
推荐引用方式 GB/T 7714	Zhang, Heng,Gao, Zeng-Qiang,Su, Xiao-Dong,et al. Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa[J]. 欧洲生化学会联合会快报,2012.
APA	Zhang, Heng,Gao, Zeng-Qiang,Su, Xiao-Dong,&Dong, Yu-Hui.(2012).Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa.欧洲生化学会联合会快报.
MLA	Zhang, Heng,et al."Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa".欧洲生化学会联合会快报 (2012).