Ultralow-power near-infrared excited neodymium-doped nanoparticles for   long-term in vivo bioimaging

doi:10.1039/c7nr00606c

CORC > 北京大学 > 化学与分子工程学院

	Ultralow-power near-infrared excited neodymium-doped nanoparticles for long-term in vivo bioimaging
	Qin, Qing-Song ; Zhang, Pei-Zhi ; Sun, Ling-Dong ; Shi, Shuo ; Chen, Nai-Xiu ; Dong, Hao ; Zheng, Xiao-Yu ; Li, Le-Min ; Yan, Chun-Hua
刊名	NANOSCALE
	2017
关键词	UP-CONVERSION NANOPHOSPHORS OPTICAL-PROPERTIES QUANTUM DOTS NANOCRYSTALS NM
DOI	10.1039/c7nr00606c
英文摘要	Lanthanide-doped luminescent nanoparticles with both emission and excitation in the near-infrared (NIR-to-NIR) region hold great promise for bioimaging. Herein, core@shell structured LiLuF4: Nd@LiLuF4 (named as Nd@Lu) nanoparticles (NPs) with highly efficient NIR emission were developed for high-performance in vivo bioimaging. Strikingly, the absolute quantum yield of Nd@Lu NPs reached as high as 32%. After coating with polyethylene glycol (PEG), the water-dispersible Nd@Lu NPs showed good bio-compatibility and low toxicity. With efficient NIR emission, the Nd@Lu NPs were clearly detectable in tissues at depths of up to 20 mm. In addition, long-term in vivo biodistribution with a high signal-to-noise ratio of 25.1 was distinctly tracked upon an ultralow-power-density excitation (10 mW cm(-2)) of 732 nmfor the first time.; NSFC [21425101, 21321001, 21371011, 21331001]; MOST of China [2014CB643800]; SCI(E); ARTICLE; 14; 4660-4664; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/474009]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Qin, Qing-Song,Zhang, Pei-Zhi,Sun, Ling-Dong,et al. Ultralow-power near-infrared excited neodymium-doped nanoparticles for long-term in vivo bioimaging[J]. NANOSCALE,2017.
APA	Qin, Qing-Song.,Zhang, Pei-Zhi.,Sun, Ling-Dong.,Shi, Shuo.,Chen, Nai-Xiu.,...&Yan, Chun-Hua.(2017).Ultralow-power near-infrared excited neodymium-doped nanoparticles for long-term in vivo bioimaging.NANOSCALE.
MLA	Qin, Qing-Song,et al."Ultralow-power near-infrared excited neodymium-doped nanoparticles for long-term in vivo bioimaging".NANOSCALE (2017).