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Hydrazide functionalized monodispersed silica microspheres: a novel probe with tunable selectivity for a versatile enrichment of phosphopeptides with different numbers of phosphorylation sites in MS analysis
Xu, Linnan ; Ma, Wen ; Shen, Sensen ; Li, Liping ; Bai, Yu ; Liu, Huwei
刊名CHEMICAL COMMUNICATIONS
2016
关键词METAL AFFINITY-CHROMATOGRAPHY MASS-SPECTROMETRY MULTIPHOSPHORYLATED PEPTIDES MAGNETIC NANOPARTICLES PHOSPHOPROTEOMICS CHEMISTRY MIXTURES SPHERES
DOI10.1039/c5cc07941a
英文摘要Hydrazide functionalized monodispersed silica microspheres (HFMSM) were developed for the enrichment of phosphopeptides for the first time. With the aid of the tunable selectivity of HFMSM, global enrichment or fractionation of phosphopeptides with different numbers of phosphorylation sites could be realized by a simple modulation of the concentrations of formic acid in buffers.; National Natural Science Foundation of China [21322505, 21175008]; Ministry of Science and Technology of China [2012YQ09019409]; SCI(E); ARTICLE; yu.bai@pku.edu.cn; 6; 1162-1165; 52
语种英语
内容类型期刊论文
源URL[http://ir.pku.edu.cn/handle/20.500.11897/438976]  
专题化学与分子工程学院
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Xu, Linnan,Ma, Wen,Shen, Sensen,et al. Hydrazide functionalized monodispersed silica microspheres: a novel probe with tunable selectivity for a versatile enrichment of phosphopeptides with different numbers of phosphorylation sites in MS analysis[J]. CHEMICAL COMMUNICATIONS,2016.
APA Xu, Linnan,Ma, Wen,Shen, Sensen,Li, Liping,Bai, Yu,&Liu, Huwei.(2016).Hydrazide functionalized monodispersed silica microspheres: a novel probe with tunable selectivity for a versatile enrichment of phosphopeptides with different numbers of phosphorylation sites in MS analysis.CHEMICAL COMMUNICATIONS.
MLA Xu, Linnan,et al."Hydrazide functionalized monodispersed silica microspheres: a novel probe with tunable selectivity for a versatile enrichment of phosphopeptides with different numbers of phosphorylation sites in MS analysis".CHEMICAL COMMUNICATIONS (2016).
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