Copper(I)-triazole dimer formation and rate acceleration in in-source   click reaction

doi:10.1039/c5ra19855k

CORC > 北京大学 > 化学与分子工程学院

	Copper(I)-triazole dimer formation and rate acceleration in in-source click reaction
	Qiu, Ran ; Luo, Hai
刊名	RSC ADVANCES
	2015
关键词	IONIZATION MASS-SPECTROMETRY DESORPTION ELECTROSPRAY-IONIZATION ATMOSPHERIC-PRESSURE LASER-ABLATION COPPER INTERMEDIATE COMPLEXES PROTEINS PAPER
DOI	10.1039/c5ra19855k
英文摘要	Besides analytical applications, ambient mass spectrometry (MS) is also a special platform to execute various chemical reactions. Chemistry in laser desorption-based, ambient MS ion sources has unique features. Previously, laser-ablated copper(I) ions were used to catalyze in-source click reactions. The advances of such in-source reaction are presented here. First, the encounter and structure elucidation of a copper(I) triazole dimer are demonstrated. Then, based on the quick appearance of such dimer in the HALDI-MS spectrum, the rate acceleration effect is studied. Last, the crystalized dimer is used to catalyze the in-flask click reaction, and confirms the proposed "di-nuclear mechanism" of the click reaction. This work is another example of how ambient in-source chemistry having unique features compares with traditional in-flask chemistry, and also shows that new insightful information can be obtained from results of ambient in-source reactions.; National Natural Science Foundation of China [20727002, 21075005]; Graduate School of Peking University (Spring); SCI(E); EI; ARTICLE; hluo@pku.edu.cn; 116; 96213-96221; 5
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/424530]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Qiu, Ran,Luo, Hai. Copper(I)-triazole dimer formation and rate acceleration in in-source click reaction[J]. RSC ADVANCES,2015.
APA	Qiu, Ran,&Luo, Hai.(2015).Copper(I)-triazole dimer formation and rate acceleration in in-source click reaction.RSC ADVANCES.
MLA	Qiu, Ran,et al."Copper(I)-triazole dimer formation and rate acceleration in in-source click reaction".RSC ADVANCES (2015).