Synthesis of fragment derivatives of delta sleep-inducing peptide (1-4)   catalyzed by enzymes in organic solvents

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	Synthesis of fragment derivatives of delta sleep-inducing peptide (1-4) catalyzed by enzymes in organic solvents
	Shen, HY ; Tian, GL ; Hong, YY ; Li, H ; Ye, YH
刊名	中国化学英文版
	2005
关键词	DSEP enzymatic synthesis organic solvent peptide SLEEP-INDUCING PEPTIDE ENZYMATIC-SYNTHESIS DIPEPTIDE PRECURSOR
英文摘要	Synthesis of two fragment derivatives of delta sleep-inducing peptide (DSIP) (1-4), Boc-Trp-Ala-Gly-GlyNH-NHPh (1) and Boc-Trp-Ala-Gly-GlyOEt (2), catalyzed by proteases via 2 + 2 or 1 + 3 synthetic routes with different protecting groups at C-terminal in organic solvents was reported. The yield of N-Boc tetrapeptide with phenylhydrazinyl protecting carboxyl group at C-terminal (1) was higher than that of N-Boc tetrapeptide ethyl ester (2) by 2+2 route. The factors influencing the synthetic yield of the fragments of DSIP (1-4) were discussed.; Chemistry, Multidisciplinary; SCI(E); 0; ARTICLE; 5; 640-642; 23
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/399452]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Shen, HY,Tian, GL,Hong, YY,et al. Synthesis of fragment derivatives of delta sleep-inducing peptide (1-4) catalyzed by enzymes in organic solvents[J]. 中国化学英文版,2005.
APA	Shen, HY,Tian, GL,Hong, YY,Li, H,&Ye, YH.(2005).Synthesis of fragment derivatives of delta sleep-inducing peptide (1-4) catalyzed by enzymes in organic solvents.中国化学英文版.
MLA	Shen, HY,et al."Synthesis of fragment derivatives of delta sleep-inducing peptide (1-4) catalyzed by enzymes in organic solvents".中国化学英文版 (2005).