WDSPdb: a database for WD40-repeat proteins

doi:10.1093/nar/gku1023

CORC > 北京大学 > 化学与分子工程学院

	WDSPdb: a database for WD40-repeat proteins
	Wang, Yang ; Hu, Xue-Jia ; Zou, Xu-Dong ; Wu, Xian-Hui ; Ye, Zhi-Qiang ; Wu, Yun-Dong
刊名	核酸研究
	2015
关键词	SER/THR-TRP TETRAD WD-REPEAT COMPLEX RESOURCE
DOI	10.1093/nar/gku1023
英文摘要	WD40-repeat proteins, as one of the largest protein families, often serve as platforms to assemble functional complexes through the hotspot residues on their domain surfaces, and thus play vital roles in many biological processes. Consequently, it is highly required for researchers who study WD40 proteins and protein-protein interactions to obtain structural information of WD40 domains. Systematic identification of WD40-repeat proteins, including prediction of their secondary structures, tertiary structures and potential hotspot residues responsible for protein-protein interactions, may constitute a valuable resource upon this request. To achieve this goal, we developed a specialized database WDSPdb (http://wu.scbb.pkusz.edu.cn/wdsp/) to provide these details of WD40-repeat proteins based on our recently published method WDSP. The WDSPdb contains 63 211 WD40-repeat proteins identified from 3383 species, including most well-known model organisms. To better serve the community, we implemented a user-friendly interactive web interface to browse, search and download the secondary structures, 3D structure models and potential hotspot residues provided by WDSPdb.; Biochemistry & Molecular Biology; SCI(E); PubMed; 3; ARTICLE; yezq@pkusz.edu.cn; wuyd@pkusz.edu.cn; D1; D339-D344; 43
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/341650]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Wang, Yang,Hu, Xue-Jia,Zou, Xu-Dong,et al. WDSPdb: a database for WD40-repeat proteins[J]. 核酸研究,2015.
APA	Wang, Yang,Hu, Xue-Jia,Zou, Xu-Dong,Wu, Xian-Hui,Ye, Zhi-Qiang,&Wu, Yun-Dong.(2015).WDSPdb: a database for WD40-repeat proteins.核酸研究.
MLA	Wang, Yang,et al."WDSPdb: a database for WD40-repeat proteins".核酸研究 (2015).