Carbon nanomaterials field-effect-transistor-based biosensors

doi:10.1038/am.2012.42

CORC > 北京大学 > 化学与分子工程学院

	Carbon nanomaterials field-effect-transistor-based biosensors
	Liu, Song ; Guo, Xuefeng
刊名	npg asia materials
	2012
关键词	biosensor carbon nanotube field-effect transistor graphene MOLECULAR ELECTRONIC DEVICES LABEL-FREE DETECTION GRAPHENE OXIDE SENSING APPLICATIONS NONCOVALENT FUNCTIONALIZATION ELECTROCHEMICAL BIOSENSORS NANOWIRE NANOSENSORS ELECTRICAL DETECTION PROTEIN ADSORPTION NANOTUBE-NETWORK
DOI	10.1038/am.2012.42
英文摘要	Carbon nanomaterials field-effect transistor (FET)-based electrical biosensors provide significant advantages over the current gold standards, holding great potential for realizing direct, label-free, real-time electrical detection of biomolecules in a multiplexed manner with ultrahigh sensitivity and excellent selectivity. The feasibility of integrating them with current complementary metal oxide semiconductor platform and a fluid handling module using standard microfabrication technology opens up new opportunities for the development of low-cost, low-noise, portable electrical biosensors for use in practical future devices. In this article, we review recent progress in the rapidly developing area of biomolecular interaction detection using FET-based biosensors based on the carbon nanomaterials single-walled carbon nanotubes (SWNTs) and graphene. Detection scenarios include DNA-DNA hybridization, DNA-protein interaction, protein function and cellular activity. In particular, we will highlight an amazing property of SWNT- or graphene-FETs in biosensing: their ability to detect biomolecules at the single-molecule level or at the single-cell level. This is due to the size comparability and the surface compatibility of the carbon nanomaterials with biological molecules. We also summarize some current challenges the scientific community is facing, including device-to-device heterogeneity and the lack of system integration for uniform device array mass production. NPG Asia Materials (2012) 4, e23; doi:10.1038/am.2012.42; published online 17 August 2012; Materials Science, Multidisciplinary; SCI(E); EI; 0; REVIEW; 8; 1-10; 4
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/313096]
专题	化学与分子工程学院工学院
推荐引用方式 GB/T 7714	Liu, Song,Guo, Xuefeng. Carbon nanomaterials field-effect-transistor-based biosensors[J]. npg asia materials,2012.
APA	Liu, Song,&Guo, Xuefeng.(2012).Carbon nanomaterials field-effect-transistor-based biosensors.npg asia materials.
MLA	Liu, Song,et al."Carbon nanomaterials field-effect-transistor-based biosensors".npg asia materials (2012).