Selectivity difference between carboxyethyl-beta-cyclodextrin and carboxymethyl-beta-cyclodextrin in enantioseparations of drugs by capillary electrophoresis | |
Ren, XQ ; Su, XD ; Huang, AJ ; Sun, YL ; Sun, ZP | |
刊名 | chromatographia |
2000 | |
关键词 | capillary electrophoresis enantiomeric separation carboxyethyl-beta-CD carboxymethyl-beta-CD CHIRAL SEPARATIONS ELECTROKINETIC CHROMATOGRAPHY ENANTIOMERIC RESOLUTION BUFFER MODIFIERS DERIVATIVES RECOGNITION SELECTOR |
DOI | 10.1007/BF02490824 |
英文摘要 | In this report the separation selectivity of carboxyethyl-beta-cyclodextrin (CE-beta-CD) and carboxymethyl-beta-cyclodextrin (CM-beta-CD) for some chiral test drugs was examined. By using CE-beta-CD as selector, nine out of 38 test drugs were resolved with resolutions greater than 0.9. By replacing CE-beta-CD with CM-beta-CD another four drugs were reserved of which only verapamil had been previously separated with CE-beta-CD. The selectivity of the two selectors differed dramatically despite their close structural resemblance.; Biochemical Research Methods; Chemistry, Analytical; SCI(E); 2; ARTICLE; 9-10; 634-637; 51 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/213705] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Ren, XQ,Su, XD,Huang, AJ,et al. Selectivity difference between carboxyethyl-beta-cyclodextrin and carboxymethyl-beta-cyclodextrin in enantioseparations of drugs by capillary electrophoresis[J]. chromatographia,2000. |
APA | Ren, XQ,Su, XD,Huang, AJ,Sun, YL,&Sun, ZP.(2000).Selectivity difference between carboxyethyl-beta-cyclodextrin and carboxymethyl-beta-cyclodextrin in enantioseparations of drugs by capillary electrophoresis.chromatographia. |
MLA | Ren, XQ,et al."Selectivity difference between carboxyethyl-beta-cyclodextrin and carboxymethyl-beta-cyclodextrin in enantioseparations of drugs by capillary electrophoresis".chromatographia (2000). |
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