A SPECULATIVE VIEW OF IMMUNE RECOGNITION

doi:10.3109/08820139409063433

CORC > 北京大学 > 化学与分子工程学院

	A SPECULATIVE VIEW OF IMMUNE RECOGNITION
	LU, NQ
刊名	immunological investigations
	1994
关键词	CLASS-II REGION HAPTEN ANTIBODY RESPONSES PIG T-LYMPHOCYTES CATALYTIC ANTIBODIES ANTIGEN PRESENTATION B-LYMPHOCYTES HISTOINCOMPATIBLE-T CELL INTERACTIONS CARRIER FUNCTION MACROPHAGES
DOI	10.3109/08820139409063433
英文摘要	The speculation that immunologically reactive haptens must be those attached to carriers' immunodominant epitopes suggests a clearer mechanism by which the mysterious hapten-carrier phenomena are generated. This review focuses on the molecular biological nature of immune recognition of hapten-protein antigens both by the T-cell and the B-cell. T and B lymphocytes specifically recognize one determinant of the same antigen molecule in two different ways and in different circumstances. The B-cell recognizes an antigen by the preliminary antigen receptors on the cell's surface, at the time it is still intact, interiorizes it and presents the processed antigenic peptide after an antigen processing procedure. In contrast, the T-cell recognizes a hidden antigenic determinant, together with portions of the MHC on the presenting cell. The immune memory is mainly directed to the hidden internal determinant of an antigen. Some aspects of the clonal selection theory of antibody formation are also discussed at the modern molecular level.; Immunology; SCI(E); PubMed; 3; ARTICLE; 1; 53-71; 23
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150300]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	LU, NQ. A SPECULATIVE VIEW OF IMMUNE RECOGNITION[J]. immunological investigations,1994.
APA	LU, NQ.(1994).A SPECULATIVE VIEW OF IMMUNE RECOGNITION.immunological investigations.
MLA	LU, NQ."A SPECULATIVE VIEW OF IMMUNE RECOGNITION".immunological investigations (1994).