Preparation of highly optically pure homochiral sulfide-containing   alcohols via oxazaborolidine-catalyzed asymmetric borane reduction of   ketones

doi:10.1002/chir.20048

CORC > 北京大学 > 化学与分子工程学院

	Preparation of highly optically pure homochiral sulfide-containing alcohols via oxazaborolidine-catalyzed asymmetric borane reduction of ketones
	Xu, JX ; Wei, TZ ; Xia, JK ; Zhang, Q ; Wu, HS
刊名	chirality
	2004
关键词	asymmetric reduction borane enantioselectivity homochirality ketone oxazaborolidine secondary alcohol LINEAR SECONDARY ALCOHOLS PROCHIRAL KETONES BAKERS-YEAST RESOLUTION PURITY
DOI	10.1002/chir.20048
英文摘要	Highly optically pure homochiral 1-(4-alkylthiophenyl) alcohols were prepared efficiently and practically via the oxazaborolidine-catalyzed asymmetric borane reduction of prochiral ketones in toluene at 25degreesC. The coordination of the sulfur atom in the ketones to the boron atom in the catalyst and borane can be inhibited under these reduction conditions. (C) 2004 Wiley-Liss, Inc.; Chemistry, Medicinal; Chemistry, Analytical; Chemistry, Organic; Pharmacology & Pharmacy; SCI(E); PubMed; 11; ARTICLE; 6; 341-346; 16
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/150261]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xu, JX,Wei, TZ,Xia, JK,et al. Preparation of highly optically pure homochiral sulfide-containing alcohols via oxazaborolidine-catalyzed asymmetric borane reduction of ketones[J]. chirality,2004.
APA	Xu, JX,Wei, TZ,Xia, JK,Zhang, Q,&Wu, HS.(2004).Preparation of highly optically pure homochiral sulfide-containing alcohols via oxazaborolidine-catalyzed asymmetric borane reduction of ketones.chirality.
MLA	Xu, JX,et al."Preparation of highly optically pure homochiral sulfide-containing alcohols via oxazaborolidine-catalyzed asymmetric borane reduction of ketones".chirality (2004).