Synthesis of molecularly imprinted polymers via ring-opening metathesis   polymerization for solid-phase extraction of bisphenol A

doi:10.1007/s00216-011-5178-x

CORC > 北京大学 > 化学与分子工程学院

	Synthesis of molecularly imprinted polymers via ring-opening metathesis polymerization for solid-phase extraction of bisphenol A
	Wang, Xiaohong ; Chen, Lirong ; Xu, Xiaojie ; Li, Yuanzong
刊名	分析化学和生物分析化学
	2011
关键词	Molecular imprinted polymer Ring-opening metathesis polymerization Solid-phase extraction PERFORMANCE LIQUID-CHROMATOGRAPHY LIVING RADICAL POLYMERIZATION OLEFIN-METATHESIS FUNCTIONALIZED MONOLITHS CATALYST WATER 2,4,6-TRICHLOROPHENOL DICYCLOPENTADIENE CHLOROPHENOLS COPOLYMERS
DOI	10.1007/s00216-011-5178-x
英文摘要	The use of molecularly imprinted polymers (MIPs) prepared by ring-opening metathesis polymerization (ROMP) for bisphenol A (BPA) was reported in this article. The resulting MIPs have high imprinting and adsorption capacities, and can be used for separation and determination of BPA in environmental water samples. The successful application of ROMP in the molecular imprinting field is described here. For the first time, two cross-linkers (dicyclopentadiene and 2,5-norbornadiene) and two Grubbs catalysts (first and second generation) were investigated to compare their effects on the binding performance of MIPs. The ROMP technique is able to create the imprinted polymers within 1 h under mild conditions. Furthermore, it can provide MIPs with obvious imprinting effects towards the template, very fast template rebinding kinetics, high binding capacity and appreciable selectivity over structurally related compounds. The adsorption process for MIPs in this study can be completed within 45 min, which is much faster than that of bulk MIPs synthesized by traditional free-radical polymerization. The resulting imprinting polymer was evaluated for its use as a sorbent support in an off-line solid-phase extraction approach to recover BPA from diluted aqueous samples. The optimized extraction protocol resulted in a reliable MISPE method suitable for selective extraction and preconcentration of BPA from tap water, human urine and liquid milk samples. This article demonstrates the practical feasibility of the MIPs prepared via ROMP as solid-phase extraction materials.; Biochemical Research Methods; Chemistry, Analytical; SCI(E); EI; PubMed; 12; ARTICLE; 4; 1423-1432; 401
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/149955]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Wang, Xiaohong,Chen, Lirong,Xu, Xiaojie,et al. Synthesis of molecularly imprinted polymers via ring-opening metathesis polymerization for solid-phase extraction of bisphenol A[J]. 分析化学和生物分析化学,2011.
APA	Wang, Xiaohong,Chen, Lirong,Xu, Xiaojie,&Li, Yuanzong.(2011).Synthesis of molecularly imprinted polymers via ring-opening metathesis polymerization for solid-phase extraction of bisphenol A.分析化学和生物分析化学.
MLA	Wang, Xiaohong,et al."Synthesis of molecularly imprinted polymers via ring-opening metathesis polymerization for solid-phase extraction of bisphenol A".分析化学和生物分析化学 (2011).