Semiparametric Bayesian analysis of accelerated failure time models with cluster structures | |
Li, Zhaonan ; Xu, Xinyi ; Shen, Junshan | |
2017 | |
关键词 | density ratio model mixture of Dirichlet processes survival analysis REGRESSION-MODELS EFFICIENT ESTIMATION DIRICHLET PROCESS CENSORED-DATA LIKELIHOOD INFERENCE MIXTURES QUANTILE PRIORS |
英文摘要 | In this paper, we develop a Bayesian semiparametric accelerated failure time model for survival data with cluster structures. Our model allows distributional heterogeneity across clusters and accommodates their relationships through a density ratio approach. Moreover, a nonparametric mixture of Dirichlet processes prior is placed on the baseline distribution to yield full distributional flexibility. We illustrate through simulations that our model can greatly improve estimation accuracy by effectively pooling information from multiple clusters, while taking into account the heterogeneity in their random error distributions. We also demonstrate the implementation of our method using analysis of Mayo Clinic Trial in Primary Biliary Cirrhosis.; National Science Foundation [DMS-1613110]; National Natural Science Foundation of China [11471024, 11171230]; SCI(E); ARTICLE; 25; 3976-3989; 36 |
语种 | 英语 |
出处 | SCI |
出版者 | STATISTICS IN MEDICINE |
内容类型 | 其他 |
源URL | [http://hdl.handle.net/20.500.11897/470392] |
专题 | 数学科学学院 |
推荐引用方式 GB/T 7714 | Li, Zhaonan,Xu, Xinyi,Shen, Junshan. Semiparametric Bayesian analysis of accelerated failure time models with cluster structures. 2017-01-01. |
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