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	A generalized hybrid algorithm for bioluminescence tomography
	Shi, Shengkun ; Mao, Heng
	2013
关键词	PERMISSIBLE SOURCE REGION PET OPET SYSTEM IMAGE-RECONSTRUCTION OPTICAL TOMOGRAPHY GRAPH CUTS SIMULATION FEASIBILITY INFORMATION MOUSE
英文摘要	Bioluminescence tomography (BLT) is a promising optical molecular imaging technique on the frontier of biomedical optics. In this paper, a generalized hybrid algorithm has been proposed based on the graph cuts algorithm and gradient-based algorithms. The graph cuts algorithm is adopted to estimate a reliable source support without prior knowledge, and different gradient-based algorithms are sequentially used to acquire an accurate and fine source distribution according to the reconstruction status. Furthermore, multilevel meshes for the internal sources are used to speed up the computation and improve the accuracy of reconstruction. Numerical simulations have been performed to validate this proposed algorithm and demonstrate its high performance in the multi-source situation even if the detection noises, optical property errors and phantom structure errors are involved in the forward imaging. (C) 2013 Optical Society of America; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318421400006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemical Research Methods; Optics; Radiology, Nuclear Medicine & Medical Imaging; SCI(E); EI; PubMed; 2; ARTICLE; 5; 709-724; 4
语种	英语
出处	EI ; PubMed ; SCI
出版者	biomedical optics express
内容类型	其他
源URL	[http://hdl.handle.net/20.500.11897/314168]
专题	数学科学学院
推荐引用方式 GB/T 7714	Shi, Shengkun,Mao, Heng. A generalized hybrid algorithm for bioluminescence tomography. 2013-01-01.

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