Thermodaynamic Origin of Cononsolvency

doi:http://meetings.aps.org/Meeting/MAR18/Session/R52.3

	Thermodaynamic Origin of Cononsolvency
	Cheng H(程贺); Ma, Changli; Cheng, He, Zuo, Taisen; Ma ZL(马长利); Zuo TS(左太森)
刊名	APS March Meeting 2018
	2018
卷号	63 期号:1 页码:R52.3
DOI	http://meetings.aps.org/Meeting/MAR18/Session/R52.3
文献子类	Proceedings Paper
英文摘要	Cononsolvency is a phenomenon for which the solubility of a polymer or protein decreases or even vanishes in the mixture of good solvents. Although it is widely used in physicochemical, green chemical and pharmaceutical industry, it’s origin is still under debates for decades. A few theoretical explanations were proposed based on experimental results on conformation variation of polymer chains on the length scale of tens of nanometer. Here, by using combined neutron total scattering and all-atom molecular dynamic simulation, we present a universal thermodynamic explanation of cononsolveny, based on strong solvent-solvent attraction. The mixed solvent structure at molecular level in a few angstroms is successfully connected to the polymer conformation with dimension around several nm. Our study opens up many directions to explore all-atom structure in macromolecular solution and the origin of its solubility.
会议地点	Los Angeles, California
语种	英语
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/287002]
专题	高能物理研究所_东莞分部高能物理研究所_实验物理中心中国科学院高能物理研究所_离退办
通讯作者	Cheng H(程贺)
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Cheng H,Ma, Changli,Cheng, He, Zuo, Taisen,et al. Thermodaynamic Origin of Cononsolvency[J]. APS March Meeting 2018,2018,63(1):R52.3.
APA	程贺,Ma, Changli,Cheng, He, Zuo, Taisen,马长利,&左太森.(2018).Thermodaynamic Origin of Cononsolvency.APS March Meeting 2018,63(1),R52.3.
MLA	程贺,et al."Thermodaynamic Origin of Cononsolvency".APS March Meeting 2018 63.1(2018):R52.3.