Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries

doi:10.1016/j.ijheh.2017.10.017

	Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries
	Hruba, F; Rentschler, G; Rodushkin, I; Cerna, M; Chen, CY; Harari, F; Harari, R; Horvat, M; Kasparova, L; Koppova, K
刊名	INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
	2018
卷号	221 期号:2 页码:223-230
关键词	Catalytic converters Traffic Cis-platinum Human Biomarkers Biomonitoring Metals Women High-resolution ICP-MS
ISSN号	1438-4639
DOI	10.1016/j.ijheh.2017.10.017
文献子类	Article
英文摘要	Background: There is little reliable information on human exposure to the metals platinum (Pt), palladium (Pd) and rhodium (Rh), despite their use in enormous quantities in catalytic converters for automobile exhaust systems. Objectives: To evaluate blood concentrations of Pt (B-Pt), Pd (B-Pd) and Rh (B-Rh) in women from six European and three non-European countries, and to identify potentially influential factors. In addition, molybdenum (Mo) and strontium (Sr) were analysed. Methods: Blood from 248 women aged 47-61 was analysed by high resolution inductively coupled plasma mass spectrometry under strict quality control. Results: The medians were: B-Pt 0.8 (range < 0.6-5.2), B-Pd < 5 (< 5-9.3), B-Rh < 0.4 (< 0.4-3.6) ng/L and BMo 2.0 (0.2-16) and B-Sr 16.6 (3.5-49) pg/L. Two women with highly elevated B-Pt (242 and 60 ng/L), previously cancer treated with cis-platinum, were not included in the data analysis. All elements varied geographically (2-3 times) (B-Pd P = 0.05; all other elements P < 0.001); variations within each area were generally 5-10 times. Traffic was not associated with increased concentrations. Conclusions: General population blood concentrations of Pt, Pd and Rh are within or below the single digit ng/L range, much lower than in most previous reports. This is probably due to improved analytical performance, allowing for more reliable information at ultra-trace levels. In general, Mo and Sr agreed with previously reported concentrations. All elements showed geographical and inter-individual variations, but no convincing relationships with self-reported traffic intensity were found. Pt from the antineoplastic drug cis-platinum it retained in the body for years.
电子版国际标准刊号	1618-131X
WOS关键词	PLASMA-MASS SPECTROMETRY ; CATALYST PRODUCTION PLANT ; TRACE-ELEMENTS ; WHOLE-BLOOD ; SWEDISH ADOLESCENTS ; GROUP METALS ; ICP-MS ; EXPOSURE ; URINE ; POPULATION
WOS研究方向	Public, Environmental & Occupational Health ; Infectious Diseases
语种	英语
WOS记录号	WOS:000429397300008
内容类型	期刊论文
源URL	[http://ir.ihep.ac.cn/handle/311005/285801]
专题	高能物理研究所_多学科研究中心
作者单位	中国科学院高能物理研究所
推荐引用方式 GB/T 7714	Hruba, F,Rentschler, G,Rodushkin, I,et al. Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,2018,221(2):223-230.
APA	Hruba, F.,Rentschler, G.,Rodushkin, I.,Cerna, M.,Chen, CY.,...&李玉锋.(2018).Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries.INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,221(2),223-230.
MLA	Hruba, F,et al."Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries".INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 221.2(2018):223-230.