The influence of the cation of quaternized chitosans on antioxidant activity

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	The influence of the cation of quaternized chitosans on antioxidant activity
	Xue, QZ; Liu, JL; Sun, HL; Dong, F; Wang, G; Qin, S; Guo, ZY; qdioqdio@yahoo.com.cn
刊名	CARBOHYDRATE POLYMERS
	2009
卷号	78 期号:3 页码:439-443
关键词	Quaternized Chitosans Antioxidant Activity Group Electronegativity
ISSN号	0144-8617
英文摘要	Various quaternized chitosans (QCSs) were synthesized according to previous method. Their reducing power and antioxidant potency against hydroxyl radicals ((OH)-O-center dot) and hydrogen peroxide (H2O2) were explored by the established systems in vitro. The QCSs exhibited markedly antioxidant activity, especially TCEDMCS, whose IC50 on hydroxyl radicals was 0.235 mg/mL. They showed 65-80% scavenging effect on hydrogen peroxide at a dose of 0.5 mg/mL. Generally, the antioxidant activity decreased in the order TCEDMCS > TBEDMCS > EDMCS > PDMCS > IBDMCS > Chitosan. Furthermore, the order of their (OH)-O-center dot and H2O2 scavenging activity was consistent with the electronegativity of different substituted groups in the QCSs. The QCSs showed much stronger antioxidant activity than that of chitosan may be due to the positive charge density of the nitrogen atoms in QCSs strengthened by the substituted groups. (C) 2009 Elsevier Ltd. All rights reserved.
学科主题	Chemistry, Applied ; Chemistry, Organic ; Polymer Science
URL标识	查看原文
资助项目	LMB
WOS记录号	WOS:000269991800010
公开日期	2011-07-03
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/5070]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	qdioqdio@yahoo.com.cn
推荐引用方式 GB/T 7714	Xue, QZ,Liu, JL,Sun, HL,et al. The influence of the cation of quaternized chitosans on antioxidant activity[J]. CARBOHYDRATE POLYMERS,2009,78(3):439-443.
APA	Xue, QZ.,Liu, JL.,Sun, HL.,Dong, F.,Wang, G.,...&qdioqdio@yahoo.com.cn.(2009).The influence of the cation of quaternized chitosans on antioxidant activity.CARBOHYDRATE POLYMERS,78(3),439-443.
MLA	Xue, QZ,et al."The influence of the cation of quaternized chitosans on antioxidant activity".CARBOHYDRATE POLYMERS 78.3(2009):439-443.