Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues

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	Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues
	Hu, WM; Xu, J; Sinkkonen, J; Wu, J; wwujun2003@yahoo.com
刊名	MINI-REVIEWS IN MEDICINAL CHEMISTRY
	2010
卷号	10 期号:1 页码:51-61
关键词	Dinoflagellate Prorocentrum Polyketide Okadaic Acid Biosynthetic Origin Inhibition To Pp1 And Pp2a Pharmacophore
ISSN号	1389-5575
英文摘要	Marine dinoflagellates of the genus Prorocentrum are famous for the production of okadaic acid (OA) and its analogues. This review covers first the source, chemistry and bioactivity of polyketides from Prorocentrum species. Then recent advances in the studies of biosynthetic origin of OA and its analogues are included. Moreover, the pharmacophore for the selective inhibition of OA to protein phosphatases types 1 (PP1) and 2A (PP2A) is highlighted.
学科主题	Chemistry, Medicinal
URL标识	查看原文
资助项目	LMB
WOS记录号	WOS:000277156100006
公开日期	2011-07-02
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/3844]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	wwujun2003@yahoo.com
推荐引用方式 GB/T 7714	Hu, WM,Xu, J,Sinkkonen, J,et al. Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues[J]. MINI-REVIEWS IN MEDICINAL CHEMISTRY,2010,10(1):51-61.
APA	Hu, WM,Xu, J,Sinkkonen, J,Wu, J,&wwujun2003@yahoo.com.(2010).Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues.MINI-REVIEWS IN MEDICINAL CHEMISTRY,10(1),51-61.
MLA	Hu, WM,et al."Polyketides from Marine Dinoflagellates of the Genus Prorocentrum, Biosynthetic Origin and Bioactivity of Their Okadaic Acid Analogues".MINI-REVIEWS IN MEDICINAL CHEMISTRY 10.1(2010):51-61.