A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample

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	A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample
	Tao, Huaming 2; Li, Yunqiu 1; Lin, Xiuping ; Zhou, Xuefeng ; Dong, Junde ; Liu, Yonghong ; Yang, Bin
刊名	NATURAL PRODUCT COMMUNICATIONS
	2018
卷号	13 期号:12 页码:1629
关键词	Marine-derived fungus Aspergillus Steroid Mycotoxins
ISSN号	1934-578X
英文摘要	Chemical investigation of the fungus Aspergillus sp. SCSIO41211 derived of mangrove sediment sample afforded a ergostane-type pentacyclic steroid, (22S, 23R)-12 alpha,14 alpha,23 alpha-trihydroxy-16,22-epoxy-ergosta-4,8-dien-3,11-dione (1), together with seven known compounds, flavacol (2), aspergilliamide (3), ochratoxin A methyl ester (4), ochratoxin A ethyl ester (5), dihydroaspyrone (6), aspilactonol E (7) and aspilactonol F (8). The structures were determined on the basis of NMR and MS analysis. The isolated compounds were tested for their antiviral activity against H3N2 and EV71 viruses, cytotoxic, and antituberculosis effects. Among them, compounds 2 and 5 showed significant cytotoxicity against ten human cancer cell lines. None of the compounds displayed a significant antiviral activity against H3N2 and EV71 viruses nor antimycobacterial activities.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/17931]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位	1.Southern Med Univ, Sch Tradit Chinese Med, Guangzhou 510515, Guangdong, Peoples R China 2.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China 3.Guilin Med Univ, Coll Pharmaceut Sci, Guilin 541004, Peoples R China
推荐引用方式 GB/T 7714	Tao, Huaming,Li, Yunqiu,Lin, Xiuping,et al. A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample[J]. NATURAL PRODUCT COMMUNICATIONS,2018,13(12):1629, 1631.
APA	Tao, Huaming.,Li, Yunqiu.,Lin, Xiuping.,Zhou, Xuefeng.,Dong, Junde.,...&Yang, Bin.(2018).A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample.NATURAL PRODUCT COMMUNICATIONS,13(12),1629.
MLA	Tao, Huaming,et al."A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample".NATURAL PRODUCT COMMUNICATIONS 13.12(2018):1629.