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	Evaluation of mesh- and binary-based contour propagation methods in 4D thoracic radiotherapy treatments using patient 4D CT images
	Ma, Yuanyuan1,2,3,4; Liu, Xinguo1,2,3; Dai, Zhongying1,2,3; He, Pengbo1,2,3; Yan, Yuanlin1,2,3,4; Shen, Guosheng1,2,3,4; Yuan, Ping1; Li, Qiang1,2,3
刊名	PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS
	2017-04-01
卷号	36页码:46-53
关键词	Contour propagation algorithm 4D radiotherapy Deformable image registration 4D CT
ISSN号	1120-1797
DOI	10.1016/j.ejmp.2017.03.005
通讯作者	Li, Qiang(liqiang@impcas.ac.cn)
英文摘要	Based on four dimensional (4D) computed tomography (CT) images, mesh-and binary-based contour propagation algorithms for 4D thoracic radiotherapy treatments were evaluated. Gross tumor volumes (GTVs), lungs, hearts and spinal cords on the CT images at the end-exhale and end-inhale phases for six patients were delineated by the physician. All volumes of interest (VOIs) were automatically propagated from the end-exhale phase to the end-inhale phase using two propagation methods. The propagated VOIs were quantitatively compared with the VOIs contoured at the end-inhale phase by the physician using Dice Similarity Coefficient (DSC), Mean Slicewise Hausdorff Distance (MSHD), Center Of Mass (COM) displacement and volume difference. A two-sided Student's t test was implemented to examine the significance of the differences between the results obtained from the two algorithms. For GTVs, statistically significant differences between the two algorithms were not observed. For all the other VOIs, the mesh-based method showed higher mean DSCs for the heart, left lung, right lung and spinal cord, lower mean MSHD for the spinal cord, lower mean COM displacement for the heart, and lower mean volume differences for the left lung, right lung and spinal cord with statistically significant differences than the binary-based method. The running time for propagation was approximately 3 s and 3 min for the mesh-and binary-based methods, respectively. Collectively, the mesh-based algorithm provides superiorities in running time and reliability for contour propagation in 4D radiotherapy. (C) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
收录类别	SCI
WOS关键词	COMPUTED-TOMOGRAPHY IMAGES ; RADIATION-THERAPY ; DEFORMABLE REGISTRATION ; CANCER RADIOTHERAPY ; SEGMENTATION ; DELINEATION ; ALGORITHM ; HEAD ; TOMOTHERAPY ; ACCURACY
WOS研究方向	Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Radiology, Nuclear Medicine & Medical Imaging
语种	英语
出版者	ELSEVIER SCI LTD
WOS记录号	WOS:000402483500006
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2558012
专题	寒区旱区环境与工程研究所
通讯作者	Li, Qiang
作者单位	1.Chinese Acad Sci, Inst Modern Phys, Lanzhou 73000, Peoples R China 2.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Peoples R China 3.Key Lab Basic Res Heavy Ion Radiat Applicat Med, Lanzhou 730000, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Ma, Yuanyuan,Liu, Xinguo,Dai, Zhongying,et al. Evaluation of mesh- and binary-based contour propagation methods in 4D thoracic radiotherapy treatments using patient 4D CT images[J]. PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,2017,36:46-53.
APA	Ma, Yuanyuan.,Liu, Xinguo.,Dai, Zhongying.,He, Pengbo.,Yan, Yuanlin.,...&Li, Qiang.(2017).Evaluation of mesh- and binary-based contour propagation methods in 4D thoracic radiotherapy treatments using patient 4D CT images.PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,36,46-53.
MLA	Ma, Yuanyuan,et al."Evaluation of mesh- and binary-based contour propagation methods in 4D thoracic radiotherapy treatments using patient 4D CT images".PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 36(2017):46-53.

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