Layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide as a robust peroxidase mimic

doi:10.1016/j.cej.2019.03.070

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	Layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide as a robust peroxidase mimic
	Chen, Chao 1,2,3,4; Wang, Yi1,3,4 ; Yang, Zhiqing 1,2,3,4; Zhang, Dun 1,3,4
刊名	CHEMICAL ENGINEERING JOURNAL
	2019-08-01
卷号	369 页码:161-169
关键词	Layered double hydroxide Mixed metal oxide Nanosheet Enzyme mimic Kinetic Colorimetric detection
ISSN号	1385-8947
DOI	10.1016/j.cej.2019.03.070
通讯作者	Wang, Yi(wangyi@qdio.ac.cn) ; Zhang, Dun(zhangdun@qdio.ac.cn)
英文摘要	Herein, we first show that layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide (MMO) nanosheets with thickness of sub-10 nm exhibit an robust peroxidase (POx) mimic activity, accelerating H2O2-mediated oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to produce a color reaction. The effect of varying the Ni/V molar ratio and heating temperature on the POx mimic activity and physicochemical properties of Ni-V MMOs has also been investigated in detail. Ni-V MMO is composed of NiO and Ni3V2O8 and under optimized conditions, Ni3V2O8 nanoparticles with particle size of sub-5 nm are well dispersed on the 2D NiO nanosheet matrix. Ni-V MMO with a Ni/V molar ratio of 3:1 calcinated at 400 degrees C shows best POx mimic activity. The catalytic mechanism was analyzed by electron spin resonance spectroscopy, which suggested that the enzyme mimic activities of Ni-V MMO originated from the decomposition of H2O2 to generate reactive (OH)-O-center dot radicals. Kinetic analysis indicates typical Michaelis-Menten catalytic behavior. The findings were used to design a colorimetric assay for H2O2, best measured at 652 nm. The method has a linear response in the 10-100 mM H2O2 concentration range, with a 5.7 mM detection limit. Benefitting from the high dispersibility and high specific surface area of the ultrathin 2D nanosheets, the method is well reproducible. It's also easily performed and highly specific. The current work can provide new strategies to construct novel LDH derived nanoenzymes for biosensor, biotechnology, and biomedicine.
资助项目	Natured Science Foundation of China[41776090] ; Natured Science Foundation of China[41476068] ; National Key Research and Development Program of China[2016YFC1400605] ; Key Research and Development Program of Shandong Province[2018GHY115038] ; AoShan Talent Program ; Qingdao National Laboratory for Marine Science and Technology
WOS研究方向	Engineering
语种	英语
出版者	ELSEVIER SCIENCE SA
WOS记录号	WOS:000463344800017
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/161173]
专题	海洋研究所_海洋腐蚀与防护研究发展中心
通讯作者	Wang, Yi; Zhang, Dun
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Environm Corros & Biofouling, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China 2.Univ Chinese Acad Sci, 19 Jia Yuquan Rd, Beijing 100039, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Open Studio Marine Corros & Protect, 1 Wenhai Rd, Qingdao 266237, Shandong, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, 7 Nanhai Rd, Qingdao 266071, Shandong, Peoples R China
推荐引用方式 GB/T 7714	Chen, Chao,Wang, Yi,Yang, Zhiqing,et al. Layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide as a robust peroxidase mimic[J]. CHEMICAL ENGINEERING JOURNAL,2019,369:161-169.
APA	Chen, Chao,Wang, Yi,Yang, Zhiqing,&Zhang, Dun.(2019).Layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide as a robust peroxidase mimic.CHEMICAL ENGINEERING JOURNAL,369,161-169.
MLA	Chen, Chao,et al."Layered double hydroxide derived ultrathin 2D Ni-V mixed metal oxide as a robust peroxidase mimic".CHEMICAL ENGINEERING JOURNAL 369(2019):161-169.