The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri

doi:10.1016/j.fsi.2017.12.064

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	The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri
	Wang, Mengqiang1 ; Wang, Lingling 2,3; Jia, Zhihao 1,4; Yi, Qilin 3; Song, Linsheng 2,3
刊名	FISH & SHELLFISH IMMUNOLOGY
	2018-03-01
卷号	74 页码:205-212
关键词	Chlamys farreri Innate immunity TLR signaling pathway
ISSN号	1050-4648
DOI	10.1016/j.fsi.2017.12.064
通讯作者	Song, Linsheng(lshsong@dlou.edu.cn)
英文摘要	Toll-like receptor (TLR) signaling pathway, composed of various components, plays pivotal roles in host innate immune defense mechanism. In the present study, twenty-nine TLR signaling pathway components, including receptors, adaptors, transduction molecules and immune effectors, were identified in Zhikong scallop Chlamys farreri via assembling and screening public available transcriptomic data and expression sequence tags (ESTs). These identified TLR signaling pathway components were constitutively expressed and detectable in various tissues, and almost all of them were highly expressed in gill and hepatopancreas. These results indicated the presence of TLR signaling pathways in both MyD88-dependent and MyD88-independent forms in scallop, and implied the diversified TLR signaling pathway in mollusk C. farreri.
资助项目	National Natural Science Foundation of China[31530069] ; National Natural Science Foundation of China[41306156] ; AoShan Talents Cultivation Program ; Qingdao National Laboratory for Marine Science and Technology[2017ASTCP-OS13] ; Modern Agro-industry Technology Research System[CARS-49]
WOS研究方向	Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences
语种	英语
出版者	ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
WOS记录号	WOS:000427344200022
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/158387]
专题	海洋研究所_实验海洋生物学重点实验室
通讯作者	Song, Linsheng
作者单位	1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Funct Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China 3.Dalian Ocean Univ, Liaoning Key Lab Marine Anim Immunol, Dalian 116023, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,et al. The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri[J]. FISH & SHELLFISH IMMUNOLOGY,2018,74:205-212.
APA	Wang, Mengqiang,Wang, Lingling,Jia, Zhihao,Yi, Qilin,&Song, Linsheng.(2018).The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri.FISH & SHELLFISH IMMUNOLOGY,74,205-212.
MLA	Wang, Mengqiang,et al."The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri".FISH & SHELLFISH IMMUNOLOGY 74(2018):205-212.