A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud

doi:10.1080/14786419.2019.1607331

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud
	Adelakun, Tiwalade A.1,2,3; Ding, Xiao 1; Ombati, Rose M.2; Zhao, Ning-Dong 1; Obodozie-Ofoegbu, Obiageri 3; Di, Ying-Tong1 ; Zhang, Yu1 ; Hao, Xiao-Jiang1
刊名	NATURAL PRODUCT RESEARCH
	2019-05-07
页码	9
关键词	Euphorbia fischeriana Steud highly oxygenated abietanes phorbol esters lysosomal biogenesis
ISSN号	1478-6419
DOI	10.1080/14786419.2019.1607331
通讯作者	Zhang, Yu(zhangyu@mail.kib.ac.cn) ; Hao, Xiao-Jiang(haoxj@mail.kib.ac.cn)
英文摘要	Twenty-two diterpenoids (1-22), including two new ones (1, a tigliane-type diterpenoid and 8, an abietane-type diterpenoid) were isolated from the roots of Euphorbia fischeriana Steud. Among them, compounds 4, 7, 12, 14-16, 19-21 are isolated from this plant for the first time. Their structures were elucidated through extensive 1D, 2D NMR and the HRESIMS data. The C-13 data of 4 is hereby presented for the first time. The macrocyclic diterpenes 1 and 2 showed marked enhancement of lysosomal biosynthesis after evaluation using lysoTracker staining method. [GRAPHICS] .
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
语种	英语
WOS记录号	WOS:000469633400001
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/67420]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Zhang, Yu; Hao, Xiao-Jiang
作者单位	1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.NIPRD, Med Chem & Qual Control Dept, Abuja, Nigeria
推荐引用方式 GB/T 7714	Adelakun, Tiwalade A.,Ding, Xiao,Ombati, Rose M.,et al. A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud[J]. NATURAL PRODUCT RESEARCH,2019:9.
APA	Adelakun, Tiwalade A..,Ding, Xiao.,Ombati, Rose M..,Zhao, Ning-Dong.,Obodozie-Ofoegbu, Obiageri.,...&Hao, Xiao-Jiang.(2019).A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud.NATURAL PRODUCT RESEARCH,9.
MLA	Adelakun, Tiwalade A.,et al."A new highly oxygenated abietane diterpenoid and a new lysosome generating phorbol ester from the roots of Euphorbia fischeriana Steud".NATURAL PRODUCT RESEARCH (2019):9.