Thermodynamic study on conformation change of carbonic anhydrase

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	Thermodynamic study on conformation change of carbonic anhydrase
	Liu, YN; Han, BX; Tan, F
刊名	CHINESE SCIENCE BULLETIN
	1998-11-01
卷号	43 期号:21 页码:1802-1805
关键词	Carbonic Anhydrase Conformation Change Dsc Thermodynamics
ISSN号	1001-6538
英文摘要	The effect of pHs on structural stability of the zinc-containing metalloenzyme carbonic anhydrase has been studied by means of differential scanning calorimetry. The rule of the conformational change for the enzyme with pH change has been found by thermodynamic analysis. The experimental results also provide valuable information: in the pH range from 5.26 to 9.04, two independent endothermal peaks were observed on DSC thermogram. It shows the existence of two structural domains in the molecule. The transition temperature and enthalpy of the two domains are different.
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000077521800009
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/74235]
专题	中国科学院化学研究所
通讯作者	Liu, YN
作者单位	Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Liu, YN,Han, BX,Tan, F. Thermodynamic study on conformation change of carbonic anhydrase[J]. CHINESE SCIENCE BULLETIN,1998,43(21):1802-1805.
APA	Liu, YN,Han, BX,&Tan, F.(1998).Thermodynamic study on conformation change of carbonic anhydrase.CHINESE SCIENCE BULLETIN,43(21),1802-1805.
MLA	Liu, YN,et al."Thermodynamic study on conformation change of carbonic anhydrase".CHINESE SCIENCE BULLETIN 43.21(1998):1802-1805.