Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior

doi:10.1002/app.32678

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	Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior
	Yan, Shifeng 1; Yin, Jingbo 1; Tang, Li 1; Chen, Xuesi 2
刊名	JOURNAL OF APPLIED POLYMER SCIENCE
	2011-02-15
卷号	119 期号:4 页码:2350-2358
关键词	Hydrogel Crosslinking Carboxymethylchitosan Hydroxyethylcellulose Methylcellulose
ISSN号	0021-8995
DOI	10.1002/app.32678
英文摘要	Novel hydrogels, physically crosslinked by hydrogen bonding of component polymers, were obtained by mixing aqueous solutions of carboxymethylchitosan (CMCS) with cellulose ethers including hydroxyethylcellulose (HEC) and methylcellulose (MC). The hydrogels were characterized by IR, XPS, WAXD, and SEM. The swelling and controlled drug release behaviors of hydrogels were also studied. The results indicate that intermacromolecular hydrogen bonding in CMCS/HEC is stronger than that in CMCS/MC. The swelling and drug release rate of hydrogels decrease as the interaction of component polymers increases. Both the swelling and drug release from hydrogels can be controlled by component polymer ratio. The hydrogels may be potential candidates for biomedical applications. VC 2010 Wiley Periodicals, Inc. J Appl Polym Sci 119: 2350-2358, 2011
语种	英语
出版者	WILEY-BLACKWELL
WOS记录号	WOS:000284233500055
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/72109]
专题	中国科学院化学研究所
通讯作者	Yin, Jingbo
作者单位	1.Shanghai Univ, Sch Mat Sci & Engn, Dept Polymer Mat, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
推荐引用方式 GB/T 7714	Yan, Shifeng,Yin, Jingbo,Tang, Li,et al. Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2011,119(4):2350-2358.
APA	Yan, Shifeng,Yin, Jingbo,Tang, Li,&Chen, Xuesi.(2011).Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior.JOURNAL OF APPLIED POLYMER SCIENCE,119(4),2350-2358.
MLA	Yan, Shifeng,et al."Novel Physically Crosslinked Hydrogels of Carboxymethyl Chitosan and Cellulose Ethers: Structure and Controlled Drug Release Behavior".JOURNAL OF APPLIED POLYMER SCIENCE 119.4(2011):2350-2358.